| Identification | More | [Name]
2-Ethoxybenzaldehyde | [CAS]
613-69-4 | [Synonyms]
2-ETHOXYBENZALDEHYDE
AKOS B029848
AKOS BBS-00003145
ASISCHEM R42365
LABOTEST-BB LT00616095
O-ETHOXYBENZALDEHYDE
SALICYLALDEHYDE ETHYL ETHER
2-ethoxy-benzaldehyd
Benzaldehyde, o-ethoxy-
O-Ethoxylbenzaldehyde
ortho-Ethoxybenzaldehyde
2-ETHOXYBENZALDEHYDE, 97+%
O-ETHOXYBENZALDEHDE
2-Ethoxybenzaldehyde ,98% | [EINECS(EC#)]
210-349-2 | [Molecular Formula]
C9H10O2 | [MDL Number]
MFCD00003316 | [Molecular Weight]
150.17 | [MOL File]
613-69-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29122990 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow to light brown liquid | [Uses]
2-Ethoxybenzaldehyde was used to study the 1,3-dipolar cycloaddition reactions. | [Synthesis Reference(s)]
Synthetic Communications, 19, p. 3407, 1989 DOI: 10.1080/00397918908052747 | [Synthesis]
The general procedure for the synthesis of 2-ethoxybenzaldehyde from o-ethoxybenzyl alcohol was as follows: first, o-ethoxybenzyl alcohol (100 mg, 0.818 mmol), SS-Pd catalyst (918 mg, containing 0.04 mmol Pd), and 3 ml of toluene were mixed and the reaction mixture was purged with molecular oxygen. Subsequently, the reaction was stirred at 110 °C for 5 h, during which the reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was cooled to room temperature, diluted with ethyl acetate and filtered through a cotton bed. The combined organic layers were concentrated by evaporation under reduced pressure and the crude product obtained was purified by silica gel (60-120 mesh) column chromatography (eluent was 95:5 hexane/ethanol solvent mixture) to give 2-ethoxybenzaldehyde (94 mg, 96% yield) as a colorless liquid. | [References]
[1] Tetrahedron Letters, 2001, vol. 42, # 31, p. 5199 - 5201
[2] Tetrahedron Letters, 2013, vol. 54, # 23, p. 2924 - 2928
[3] Tetrahedron Letters, 2011, vol. 52, # 38, p. 4954 - 4956
[4] Canadian Journal of Chemistry, 2008, vol. 86, # 8, p. 782 - 790 |
|
|