| Identification | More | [Name]
2-Morpholinoethanol | [CAS]
622-40-2 | [Synonyms]
2-(4-MORPHOLINO)ETHANOL
2-MORPHOLIN-4-YL-ETHANOL
2-MORPHOLINOETHANOL
2-N-MORPHOLINOETHANOL
4-(2-HYDROXYETHYL)MORPHOLINE
4-MORPHOLINEETHANOL
4-MORPHOLINOETHANOL
AKOS BBS-00004369
AKOS MSC-0730
Morpholine ethanol
MORPHOLINOETHANOL
N-(2-Hydroxgethyl)moypholine
N-(2-HYDROXYETHYL)MORPHOLINE
N-B-HYDROXYETHYLMORPHOLINE
N-HYDROXYETHYL MORPHOLINE
TIMTEC-BB SBB004221
2-(4-Morpholinyl)-1-ethanol
2-(4-Morpholinyl)ethanol
2-(morpholinyl)-ethano
2-morpholino-ethano | [EINECS(EC#)]
210-734-5 | [Molecular Formula]
C6H13NO2 | [MDL Number]
MFCD00006180 | [Molecular Weight]
131.17 | [MOL File]
622-40-2.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS TO YELLOW LIQUID | [Melting point ]
-1 °C
| [Boiling point ]
227 °C757 mm Hg(lit.)
| [density ]
1.083 g/mL at 25 °C(lit.)
| [vapor pressure ]
2.44-7Pa at 20-25℃ | [refractive index ]
n20/D 1.476(lit.)
| [Fp ]
211 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
14.88±0.10(Predicted) | [color ]
Clear colorless to yellow | [PH]
10.7 (100g/l, H2O, 20℃) | [explosive limit]
1.5-9.8%(V) | [Water Solubility ]
miscible | [BRN ]
104375 | [Henry's Law Constant]
1.4×103 mol/(m3Pa) at 25℃, Du et al. (2017) | [InChI]
1S/C6H13NO2/c8-4-1-7-2-5-9-6-3-7/h8H,1-6H2 | [InChIKey]
KKFDCBRMNNSAAW-UHFFFAOYSA-N | [SMILES]
OCCN1CCOCC1 | [LogP]
-1.32 at 25℃ | [CAS DataBase Reference]
622-40-2(CAS DataBase Reference) | [NIST Chemistry Reference]
4-Morpholineethanol(622-40-2) | [EPA Substance Registry System]
622-40-2(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H319 | [Precautionary statements ]
P264-P280-P305+P351+P338-P337+P313 | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
1
| [RTECS ]
QE3510000
| [F ]
10-23 | [TSCA ]
Yes | [REACH Registrations]
Active | [HS Code ]
29349990 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR COLOURLESS TO YELLOW LIQUID | [Uses]
4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu lture/DNA.
| [Definition]
ChEBI: A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035 | [Flammability and Explosibility]
Nonflammable | [References]
[1] Journal of the Indian Chemical Society, 1989, vol. 66, # 5, p. 316 - 318
[2] Patent: WO2014/12360, 2014, A1. Location in patent: Paragraph 00498
[3] Patent: US2015/87639, 2015, A1. Location in patent: Paragraph 0849; 0850
[4] Patent: TWI607995, 2017, B. Location in patent: Page/Page column 180
[5] Journal of Organic Chemistry, 2018, vol. 83, # 24, p. 15333 - 15346 |
|
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Alfa Aesar
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Energy Chemical
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