| Identification | More | [Name]
1-Chloro-3-iodobenzene | [CAS]
625-99-0 | [Synonyms]
1-CHLORO-3-IODOBENZENE
3-CHLOROIODOBENZENE
M-CHLOROIODOBENZENE
M-IODOCHLOROBENZENE
1-chloro-3-iodo-benzen
3-Chloro-1-iodobenzene
3-Iodochlorobenzene
m-Chlorophenyl iodide
1-Chloro-3-iodobenzene,98%
1-Chloro-3-iodopropane 98% stabilized
3-Chloroiodobenzene (stabilized with Copper chip)
1-Iodo-3-chlorobenzene | [EINECS(EC#)]
210-920-6 | [Molecular Formula]
C6H4ClI | [MDL Number]
MFCD00001046 | [Molecular Weight]
238.45 | [MOL File]
625-99-0.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
T | [HazardClass ]
IRRITANT | [HS Code ]
29039990 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear light yellow liquid | [Uses]
suzuki reaction | [Synthesis Reference(s)]
Synthetic Communications, 11, p. 639, 1981 DOI: 10.1080/00397918108063637 | [General Description]
The multiple-quantum proton NMR spectra of 3-chloroiodobenzene was studied. | [Synthesis]
General procedure for the synthesis of m-chloroiodobenzene from 3-chlorophenylboronic acid: a mixture of arylboronic acid (0.55 mmol), KF (96 mg, 1.65 mmol) and I2 (127 mg, 0.50 mmol) in 1,4-dioxane (5 mL) was stirred and reacted for 1 hr at 80 °C. After completion of the reaction, the mixture was filtered through a silica gel column and eluted with ether (10 mL). Subsequently, the solvent was removed by rotary evaporator. For further purification, the target product, m-chloroiodobenzene, was isolated by silica gel column chromatography using petroleum ether/ether (98:2) as eluent. | [References]
[1] Chemistry - A European Journal, 2011, vol. 17, # 20, p. 5652 - 5660
[2] Tetrahedron Letters, 2015, vol. 56, # 9, p. 1122 - 1123
[3] Synlett, 1998, # 2, p. 141 - 142
[4] Synlett, 2014, vol. 25, # 7, p. 995 - 1000 |
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