| Identification | Back Directory | [Name]
oxytocin, Asp(5)- | [CAS]
65907-78-0 | [Synonyms]
Asp5-Oxytocin
oxytocin, Asp(5)-
Oxytocin, 5-L-aspartic acid- (9CI)
[Asp5]-OxytocinQ: What is
[Asp5]-Oxytocin Q: What is the CAS Number of
[Asp5]-Oxytocin | [Molecular Formula]
C43H65N11O13S2 | [MDL Number]
MFCD34473391 | [MOL File]
65907-78-0.mol | [Molecular Weight]
1008.17 |
| Chemical Properties | Back Directory | [Boiling point ]
1513.9±65.0 °C(Predicted) | [density ]
1.281±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.02±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Cys-Tyr-Ile-Gln-Asp-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6) | [Major Application]
pharmaceutical small molecule |
| Hazard Information | Back Directory | [Uses]
[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin causes uterine contractions in vitro, enhanced by Mg2+. [Asp5]-Oxytocin has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic[1]. | [References]
[1] Walter R, et al. [5-Aspartic acid]-oxytocin: first 5-position neurohypophyseal hormone analogue possessing significant biological activity. J Am Chem Soc. 1978;100(3):792-793. DOI:10.1021/ja00471a053 |
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