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698999-09-6

698999-09-6 Structure

698999-09-6 Structure
IdentificationBack Directory
[Name]

5'-CHLORO-5'-DEOXYADENOSINE HYDRATE, 97%
[CAS]

698999-09-6
[Synonyms]

[Molecular Formula]

C10H12ClN5O3.H2O
[MDL Number]

MFCD03427103
[MOL File]

698999-09-6.mol
[Molecular Weight]

303.705
Chemical PropertiesBack Directory
[Melting point ]

187 °C (exothermic decomp onset @144.5 C)(lit.)
[storage temp. ]

2-8°C
[solubility ]

DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.5 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501
[Hazard Codes ]

T
[Risk Statements ]

25
[Safety Statements ]

45
[RTECS ]

AU7357200
Hazard InformationBack Directory
[Description]

5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5’-adenosyl)-L-methionine (SAM; Item No. 13956) can be converted to 5’-chloro-5’-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase.1 Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A (Item No. 10007311) in the marine bacterium S. tropica.1WARNING This product is not for human or veterinary use.
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