| Identification | Back Directory | [Name]
ISOXANTHOHUMOL | [CAS]
70872-29-6 | [Synonyms]
Is0xanthohumol
Isoxanthohunol
lsoxanthohumol
ISOXANTHOHUMOL(P)
(?)-Isoxanthohumol
(-)-Isoxanthohumol
(2S)-Isoxanthohumol
Isoxanthohumol, (2S)-
Isoxanthohumol, 98%, from Humulus lupulus
(S)-7-Hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one
7-HYDROXY-2-(4-HYDROXYPHENYL)-5-METHOXY-8-(3-METHYLBUT-2-ENYL)-2,3-DIHYDROCHROMEN-4-ONE
(2S)-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-, (2S)- | [Molecular Formula]
C21H22O5 | [MDL Number]
MFCD00238718 | [MOL File]
70872-29-6.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Melting point ]
196-208℃ | [Boiling point ]
585.8±50.0 °C(Predicted) | [density ]
1.245±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder to crystal | [pka]
7.90±0.40(Predicted) | [color ]
White to Orange to Green | [λmax]
325nm(lit.) | [LogP]
5.070 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from hops. | [Uses]
(-)-Isoxanthohumol is a structural analog of xanthohumol that possesses anti-microbial activity. Also, it exhibits diverse biological activities, e.g. antitumor, antiiflammatory, antioxidant and antiangiogenic. | [target]
P450 (e.g. CYP17) | JAK | STAT | TGF-β/Smad | HSV | TNF-α | Akt | ERK | ROS |
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