| Identification | Back Directory | [Name]
Phenol, 4-[(4-imidazo[1,2-a]pyridin-3-yl-2-thiazolyl)amino]- | [CAS]
792898-18-1 | [Synonyms]
JNJ-1289
Phenol, 4-[(4-imidazo[1,2-a]pyridin-3-yl-2-thiazolyl)amino]- | [Molecular Formula]
C16H12N4OS | [MOL File]
792898-18-1.mol | [Molecular Weight]
308.36 |
| Hazard Information | Back Directory | [Uses]
JNJ-1289 is a potent, selective, competitive and allosteric human spermine oxidase (hSMOX) inhibitor (IC50: 50 nM). JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers[1]. | [References]
[1] Elsie Diaz, et al. B Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Commun Biol. 2022 Aug 5;5(1):787. DOI:10.1038/s42003-022-03735-9 |
|
|