| Identification | Back Directory | [Name]
1H-Indole-3-acetamide, N-[(4-methylphenyl)methyl]-α-oxo- | [CAS]
852367-46-5 | [Synonyms]
WAY-270250
1H-Indole-3-acetamide, N-[(4-methylphenyl)methyl]-α-oxo- | [Molecular Formula]
C18H16N2O2 | [MOL File]
852367-46-5.mol | [Molecular Weight]
292.34 |
| Chemical Properties | Back Directory | [Melting point ]
184-186 °C(Solv: ethanol (64-17-5)) | [density ]
1?+-.0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.66±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
IGF-1R/SRC-IN-1 (Compound 3b) is an inhibitor for IGF-1R (IC50 is 63 μM) and SRC[1]. | [References]
[1] Schmidt S, et al., Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2-(1H-indol-3-yl)-2-oxoacetohydrazide structure. Eur J Med Chem. 2011 Jul;46(7):2759-69. DOI:10.1016/j.ejmech.2011.03.065 |
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