| Identification | Back Directory | [Name]
2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleaceticacid | [CAS]
853929-59-6 | [Synonyms]
OGT 2115
(E)-2-(2-(4-(3-(4-Bromophenyl)acrylamido)-3-fluorophenyl)benzo[d]oxazol-5-yl)acetic acid
2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleaceticacid
5-Benzoxazoleacetic acid, 2-[4-[[3-(4-bromophenyl)-1-oxo-2-propen-1-yl]amino]-3-fluorophenyl]- | [Molecular Formula]
C24H16BrFN2O4 | [MDL Number]
MFCD12828743 | [MOL File]
853929-59-6.mol | [Molecular Weight]
495.3 |
| Chemical Properties | Back Directory | [Boiling point ]
685.9±55.0 °C(Predicted) | [density ]
1.574±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 10 mM in DMSO | [form ]
Powder | [pka]
3.85±0.30(Predicted) | [color ]
White to yellow | [InChI]
InChI=1S/C24H16BrFN2O4/c25-17-6-1-14(2-7-17)4-10-22(29)27-19-8-5-16(13-18(19)26)24-28-20-11-15(12-23(30)31)3-9-21(20)32-24/h1-11,13H,12H2,(H,27,29)(H,30,31) | [InChIKey]
LKBXWNYXDMSFQU-UHFFFAOYSA-N | [SMILES]
O1C2=CC=C(CC(O)=O)C=C2N=C1C1=CC=C(NC(=O)C=CC2=CC=C(Br)C=C2)C(F)=C1 |
| Hazard Information | Back Directory | [Uses]
OGT 2115 is an antiangiogenic heparanase inhibiting compound. | [in vivo]
When administered to mice, OGT 2115 (Compound 12d) shows a plasma concentration of ~10x the heparanase IC50 following oral dosing at 20 mg/kg[1]. | [storage]
Store at RT |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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