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862825-89-6

862825-89-6 Structure

862825-89-6 Structure
IdentificationBack Directory
[Name]

2-((1H-indol-3-yl)thio)-N-(2-ethoxyphenyl)acetamide
[CAS]

862825-89-6
[Synonyms]

RSV-IN-4
2-((1H-indol-3-yl)thio)-N-(2-ethoxyphenyl)acetamide
Acetamide, N-(2-ethoxyphenyl)-2-(1H-indol-3-ylthio)-
[Molecular Formula]

C18H18N2O2S
[MOL File]

862825-89-6.mol
[Molecular Weight]

326.41
Chemical PropertiesBack Directory
[Boiling point ]

563.6±35.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[pka]

13.20±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

RSV-IN-4 (Compound 2) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza virus A (IAV). RSV-IN-4 shows anti-RSV activity (EC50?=?11.76?μM)[1].
[References]

[1] Guo-Ning Zhang, et al. Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A. Eur J Med Chem. 2020 Jan 15;186:111861. DOI:10.1016/j.ejmech.2019.111861
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