| Identification | Back Directory | [Name]
Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester | [CAS]
886053-73-2 | [Synonyms]
NY2267
c-Myc,inhibit,NY2267,Inhibitor,interaction,NY 2267,Myc,Max,NY-2267
Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester | [Molecular Formula]
C38H43N3O6 | [MDL Number]
MFCD34179558 | [MOL File]
886053-73-2.mol | [Molecular Weight]
637.76 |
| Chemical Properties | Back Directory | [Boiling point ]
842.3±65.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Oil | [pka]
14.02±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 µM[1]. NY2267 strongly inhibits oncogenic transformation induced by Myc[1]. | [Uses]
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation[1]. | [References]
[1]. Yang Xu,et al. A credit-card library approach for disrupting protein-protein interactions. Bioorg Med Chem. 2006 Apr 15;14(8):2660-73. |
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