| Identification | Back Directory | [Name]
Lipoamido-PEG3-Azide | [CAS]
890016-39-4 | [Synonyms]
LA-PEG3-N3
LIPOAMIDO-PEG3-N3
Lipoamido-PEG4-azide
Lipoamido-PEG3-Azide | [Molecular Formula]
C16H30N4O4S2 | [MDL Number]
MFCD28334509 | [MOL File]
890016-39-4.mol | [Molecular Weight]
406.564 |
| Hazard Information | Back Directory | [Description]
Lipoamido-PEG3-azide is a PEG linker comprised of a lipoamide group and a terminal azide group. The azide group can participate in copper-catalyzed Click Chemistry reactions with alkynes, DCBO and BCN reagents to form triazole moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
Lipoamido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] H. Tetsuo Uyeda, et al. Synthesis of surface ligands to prepare hydrophilic and biologically compatible quantum dots. doi: 10.1117/12.590494 |
|
|