| Identification | Back Directory | [Name]
OrfaMide A | [CAS]
939960-34-6 | [Synonyms]
OrfaMide A
L-Valine, N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-alloisoleucyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-, (10→3)-lactone | [Molecular Formula]
C64H114N10O17 | [MDL Number]
MFCD33021587 | [MOL File]
939960-34-6.mol | [Molecular Weight]
1295.67 |
| Chemical Properties | Back Directory | [Boiling point ]
1503.0±65.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
4.43±0.10(Predicted) | [Sequence]
{3-hydroxy-1-oxotetradecyl}-Leu-Glu-Thr-Ile-Leu-Ser-Leu-Leu-Ser-Val (Lactam bridge: Thr3-Val10) |
| Hazard Information | Back Directory | [Uses]
Orfamide A is a possible antifungal agent. Orfamide A is the major component of a family of cyclic lipopeptides produced by Pseudomonas fluorescens, reported in 2007. | [Uses]
Orfamide A is the major component of a family of cyclic lipopeptides produced by Pseudomonas fluorescens, reported in 2007. The orfamides were discovered by employing genomic analysis with an isotope-guided fractionation to identify metabolites produced by orphan gene clusters containing non-ribosomal peptide synthetases. Orfamide A has received scant investigation of its bioprofile but appears to be a selective antifungal agent. Uniquely, orfamide A lyses zoospores of the oomycete, Phytophthora ramorum, the cause of sudden oak death. Orfamide A has a profound effect on the swarming motility of bacteria on agar surfaces. |
|
| Company Name: |
Lynnchem
|
| Telephone: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
TargetMol
|
| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
|