| Identification | More | [Name]
4'-tert-Butylacetophenone | [CAS]
943-27-1 | [Synonyms]
1-[4-(TERT-BUTYL)PHENYL]ETHAN-1-ONE
4'-TERT-BUTYLACETOPHENONE
4-TERT-BUTYLACETOPHENONE
ASISCHEM D29255
P-T-BUTYLACETOPHENONE
1-(4-tert-Butylphenyl)ethanone
1-[4-(1,1-dimethylethyl)phenyl]-ethanon
1-[4-(1,1-dimethylethyl)phenyl]-Ethanone
4'-t-Butylacetophenone
Acetophenone, 4'-tert-butyl-
Ethanone,1-[4-(1,1-dimethylethyl)phenyl]-
p-tert-Butylacetophenone
4'-tert-Butylacetophenone,98%
PHENOMUSCOL
p-tert-Butylacetophenon
4-TERT-BUTYLACETOPHENONE/4-ISOBUTYL ACETOPHENONE
4''-TERT-BUTYLACETOPHENONE 98%
1-(4-tertbutylpheny)ethanone | [EINECS(EC#)]
213-399-3 | [Molecular Formula]
C12H16O | [MDL Number]
MFCD00017256 | [Molecular Weight]
176.25 | [MOL File]
943-27-1.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Melting point ]
17-18 °C (dimorphic)(lit.)
| [Boiling point ]
107-108 °C5 mm Hg(lit.)
| [density ]
0.964 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.52(lit.)
| [Fp ]
86 °F
| [storage temp. ]
Flammables area | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Liquid | [color ]
Clear colorless | [Specific Gravity]
0.964 | [Water Solubility ]
insoluble | [Cosmetics Ingredients Functions]
PERFUMING | [InChI]
1S/C12H16O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-8H,1-4H3 | [InChIKey]
UYFJYGWNYQCHOB-UHFFFAOYSA-N | [SMILES]
CC(=O)c1ccc(cc1)C(C)(C)C | [LogP]
3.521 (est) | [CAS DataBase Reference]
943-27-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethanone, 1-[4-(1,1-dimethylethyl)phenyl]-(943-27-1) | [EPA Substance Registry System]
943-27-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R10:Flammable.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S29:Do not empty into drains .
S33:Take precautionary measures against static discharges .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 1224 3/PG 3
| [WGK Germany ]
2
| [TSCA ]
T | [HazardClass ]
3.2 | [PackingGroup ]
III | [HS Code ]
29143990 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Flam. Liq. 3 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
4-tert-Butylacetophenone is an Impurity arising in the synthesis of Ebastine (E320000). Ebastine Impurity B. | [General Description]
4′-tert-Butylacetophenone is a para-substituted acetophenone. | [Synthesis]
p-Tert-butyl acetophenone was prepared as follows: in a 2 ml reaction vial 2-(4-(tert-butyl)phenyl)propan-2-ol (59.4 mg, 0.3 mmol), AgNO3 (1.6 mg, 3 mol%), Bi(OTf)3 (6 mg, 3 mol%) and K2S2O8 (245.8 mg. 3eq), and finally 2 wt% aqueous DAPGS-750-M (0.6 ml, |
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