- 4-tert-Butylphenylboronic acid
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- $34.00 / 1kg
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2025-09-25
- CAS:123324-71-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 4-tert-Butylphenylboronic acid Basic information |
| | 4-tert-Butylphenylboronic acid Chemical Properties |
| Melting point | 191-196 °C (lit.) | | Boiling point | 296.7±33.0 °C(Predicted) | | density | 1.02±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | Crystalline Powder | | pka | 8.79±0.10(Predicted) | | color | White to off-white | | BRN | 5330959 | | InChI | InChI=1S/C10H15BO2/c1-10(2,3)8-4-6-9(7-5-8)11(12)13/h4-7,12-13H,1-3H3 | | InChIKey | MNJYZNVROSZZQC-UHFFFAOYSA-N | | SMILES | B(C1=CC=C(C(C)(C)C)C=C1)(O)O | | CAS DataBase Reference | 123324-71-0(CAS DataBase Reference) |
| | 4-tert-Butylphenylboronic acid Usage And Synthesis |
| Chemical Properties | white to off-white crystalline powder | | Uses | suzuki reaction | | Uses | 4-t-Butylphenylboronic acid is a cross-coupling building block used in the preparation of tetracyclnes and tetracycline derivatives. | | Uses | Cross-coupling building block used in synthesis of tetracycline derivatives. | | Synthesis | 4-tert-butylbromobenzene was used as starting material and 4-tert-butylphenylboronic acid (4b) was synthesized according to the method described in literature [22] in 72.8% reaction yield. The resulting product was a white solid with a melting point of 158-160 °C (literature value: 160 °C). The structure of the product was confirmed by 1H NMR spectrum (CD3Cl as solvent, 300 MHz): δ 8.17 (d, 2H, J = 6.6 Hz), 7.42-7.54 (m, 2H), 1.38 (s, 9H). | | References | [1] Tetrahedron Letters, 2003, vol. 44, # 30, p. 5747 - 5750
[2] Macromolecules, 2003, vol. 36, # 7, p. 2327 - 2332
[3] Organic and Biomolecular Chemistry, 2012, vol. 10, # 33, p. 6693 - 6704
[4] Dyes and Pigments, 2012, vol. 95, # 3, p. 679 - 688
[5] Journal of the Chemical Society. Perkin Transactions 2, 2001, # 11, p. 2166 - 2173 |
| | 4-tert-Butylphenylboronic acid Preparation Products And Raw materials |
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