1303512-02-8
中文名称
1303512-02-8
英文名称
1303512-02-8
CAS
1303512-02-8
分子式
C22H28ClN3O4
分子量
433.93
MOL 文件
1303512-02-8.mol
更新日期
2024/12/13 09:53:02
1303512-02-8 结构式
基本信息
中文别名
化合物IZILENDUSTAT化合物T001-00000002
4-((1-(4-氯苄基)-3-羟基-2-氧-2-氧-1,2-二氢吡啶-4-基)甲基)哌嗪-1-甲酸叔丁酯
英文别名
Izilendustattert-butyl 4-((1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydr
tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate
tert-butyl 4-((1-(4-chlorobenzyl)-3-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)methyl)piperazine-1-carboxylate
4-[1-(4-Chloro-benzyl)-3-hydroxy-2-oxo-1,2-dihydro-pyridin-4-ylmethyl]-piperazine-1-carboxylic acid tert-butyl ester
1-Piperazinecarboxylic acid, 4-[[1-[(4-chlorophenyl)methyl]-1,2-dihydro-3-hydroxy-2-oxo-4-pyridinyl]methyl]-, 1,1-dimethylethyl ester
inmmune response,HIF-PH,colitis,prolyl hydroxylase,Inhibitor,HIF-2,HIFs,Hypoxia-inducible factors,inflammatory bowel diseases,HIF/HIF Prolyl-Hydroxylase,Izilendustat,inhibit,HIF- lα
物理化学性质
沸点597.8±50.0 °C(Predicted)
密度1.302±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO : 25 mg/mL (57.61 mM; ultrasonic and warming and heat to 60°C)
酸度系数(pKa)8.96±0.53(Predicted)
形态Solid
颜色White to off-white