1835759-75-5
中文名称
丙烯酸琥珀酰亚胺-三聚乙二醇-丙酸叔丁酯
英文名称
t-Butoxycarbonyl-PEG4-NHS ester
CAS
1835759-75-5
分子式
C20H33NO10
分子量
447.477
MOL 文件
1835759-75-5.mol
1835759-75-5 结构式
基本信息
中文别名
丙烯酸琥珀酰亚胺-三聚乙二醇-丙酸叔丁酯 英文别名
OtBu-PEG4-SPACAS_1835759-75-5
Boc-PEG4-C2-NHS ester
NHS ester-PEG3-t-butyl ester
t-Butoxycarbonyl-PEG4-NHS ester
4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) 16-(2,5-dioxo-1-pyrrolidinyl) ester
物理化学性质
沸点528.4±60.0 °C(Predicted)
密度1.21±0.1 g/cm3(Predicted)
形态Viscous Liquid
颜色Colorless to light yellow
应用领域
用途一
t-Butoxycarbonyl-PEG4-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.