1913269-12-1
1913269-12-1 结构式
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2026/06/05 | HY-15465B | 1913269-12-1 KN-93 phosphate | 1913269-12-1 | 1 mg | 435元 |
| 2026/06/05 | HY-15465B | 1913269-12-1 KN-93 phosphate | 1913269-12-1 | 5 mg | 877元 |
| 2026/06/05 | HY-15465B | 1913269-12-1 KN-93 phosphate | 1913269-12-1 | 10 mM * 1 mL in DMSO | 1156元 |
常见问题列表
Ki: 370 nM (CaMK-II)
After 2 days of KN-93 treatment, 95% of cells are arrested in G1. G1 arrest is reversible; 1 day after KN-93 release, a peak of cells had progressed into S and G2-M. KN-93 also blocks cell growth stimulated by basic fibroblast growth factor, platelet-derived growth factor-BB, and epidermal growth factor in NIH 3T3 fibroblasts. KN-93 inhibits the H + , K + -ATPase activity but strongly dissipates the proton gradient formed in the gastric membrane vesicles and reduces the volume of luminal space. KN-93 (0.5 μM) prevents increased LV developed pressure during action potential prolongation and early afterdepolarizations. Ca 2+ -independent CaM kinase activity is increased during early afterdepolarizations and this increase is prevented by KN-93.