1956426-56-4
1956426-56-4 结构式
基本信息
KN-93 HCl
KN93 hydrochloride
KN 93 hydrochloride
KN-93 (hydrochloride)
物理化学性质
DMSO:20.5(Max Conc. mg/mL);38.14(Max Conc. mM)
Water:0.45(Max Conc. mg/mL);0.84(Max Conc. mM)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/12/22 | HY-15465A | 化合物 T21557 KN-93 hydrochloride | 1956426-56-4 | 1mg | 558元 |
| 2025/12/22 | HY-15465A | 化合物 T21557 KN-93 hydrochloride | 1956426-56-4 | 5mg | 1100元 |
| 2025/12/22 | HY-15465A | 化合物 T21557 KN-93 hydrochloride | 1956426-56-4 | 10mM * 1mLin DMSO | 1301元 |
常见问题列表
Ki: 370 nM (CaMK-II)
After 2 days of KN-93 treatment, 95% of cells are arrested in G1. G1 arrest is reversible; 1 day after KN-93 release, a peak of cells had progressed into S and G2-M. KN-93 also blocks cell growth stimulated by basic fibroblast growth factor, platelet-derived growth factor-BB, and epidermal growth factor in NIH 3T3 fibroblasts. KN-93 inhibits the H + , K + -ATPase activity but strongly dissipates the proton gradient formed in the gastric membrane vesicles and reduces the volume of luminal space. KN-93 (0.5 μM) prevents increased LV developed pressure during action potential prolongation and early afterdepolarizations. Ca 2+ -independent CaM kinase activity is increased during early afterdepolarizations and this increase is prevented by KN-93.