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Ciprofloxacin hydrochloride

Ciprofloxacin hydrochloride Struktur
93107-08-5
CAS-Nr.
93107-08-5
Englisch Name:
Ciprofloxacin hydrochloride
Synonyma:
CIPROFLOXACIN HCL;CIPROFLOXACIN HYDROCHLORIDE;1-Cyclopropyl-6-fluoro;1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride;Cyproxan;BAY-o-9867;Bay-09867 (hydrochloride);Clprofloxacin hydrochloride;Ciprofloxacin hydrochloride
CBNumber:
CB02130396
Summenformel:
C17H18FN3O3.HCl
Molgewicht:
367.8
MOL-Datei:
93107-08-5.mol
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Ciprofloxacin hydrochloride Eigenschaften

Schmelzpunkt:
>300 ºC
storage temp. 
Sealed in dry,Room Temperature
Löslichkeit
insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic
Aggregatzustand
crystalline solid
Farbe
White to off-white
BCS Class
3
InChI
InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N
SMILES
O=C(O)C1C(=O)C2=CC(=C(C=C2N(C2CC2)C=1)N1CCNCC1)F.[H]Cl
CAS Datenbank
93107-08-5
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 24/25
HS Code  29339900
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Ciprofloxacin hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-bacterial

Trademarks

Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).

Synthese

The preparation method of ciprofloxacin HCl, its step is as follows:
a) cyclopropyl carboxylic acid is added in the organic solvent, and the adding piperazine, reacted 3～8 hours down as acid binding agent with alkali at 60～120 ℃, the monitoring cyclopropyl carboxylic acid is residual less than 2% o'clock termination reaction, stirring is cooled to 0～30 ℃, leaves standstill suction filtration;
b) add water and hydrochloric acid in the products therefrom toward a) step, under agitation be warming up to molten clearly, add activated carbon decolorizing, filtered while hot, and transfer filtrate pH to 2～4 with hydrochloric acid, and the cooling crystallization filters, rinsing, and drying makes ciprofloxacin HCl.

Ciprofloxacin hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2,4-Dichloro-5-fluoroacetophenone

Downstream Produkte

Decarboxy Ciprofloxacin Ciprofloxacin

Ciprofloxacin hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 387)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Huajiu Pharmaceutical Technology Co.,Ltd. 027-59225746 18062681621
 730880265@qq.com China 4800 58
HIGH HOPE INTERNATIONAL GROUP JIANGSU MEDICINES AND HEALTH PRODUCTS IMPORT AND EXPORT CORPORATION 025-84691373 15312418043
 yxq@mehecojs.com China 117 58
Hubei widely chemical technology Co., Ltd. 027-83991130 18627774460
 1718093273@QQ.COM China 1618 58
Jiangsu Rongshuo Pharmaceutical Co., Ltd 0000-15105138935 15105138935
 2622104407@qq.com China 99 58
Shandong Qingxu Biotechnology Co., Ltd. 18039551173 18039551173
 3066129641@qq.COM China 270 58
J & K SCIENTIFIC LTD. 18210857532 18210857532
 jkinfo@jkchemical.com China 96815 76
Syntechem Co.,Ltd
info@syntechem.com China 12973 57
China Langchem Inc. 0086-21-58956006
China 7798 57
Hunan Hui Bai Shi Biotechnology Co., Ltd. 0731-85526065 13308475853
 ivy@hnhbsj.com China 7236 62
BioBioPha Co., Ltd. 0871-65217109
y.liu@mail.biobiopha.com China 5641 65

93107-08-5()Verwandte Suche:

2,6-Dimethyloct-7-en-2-ol Ciprofloxacin hydrochloride ISOPROPYLHYDRAZINE HYDROCHLORIDE Quinclorac Topotecan hydrochloride Piperazine ferulate 2-Piperazin-1-ylethylamin Ciprofloxacin hydrochloride hydrate Ciprofloxacin lactate Ciprofloxacin Norfloxacin Isochinolin Tetracyclin Paracetamol Clindamycin Wasserstoff Fluor fluoro jade
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride
  • 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
  • 3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1)
  • CIPROFLOXACIN HYDROCHLORIDE
  • BAY-o-9867
  • Cyproxan
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride
  • Clprofloxacin hydrochloride
  • 1-Cyclopropyl-6-fluoro
  • Ciprofloxacin hydrochloride CAS 93107-08-5
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride
  • Bay-09867 (hydrochloride)
  • Enrofloxacin EP Impurity BQ: What is Enrofloxacin EP Impurity B Q: What is the CAS Number of Enrofloxacin EP Impurity B
  • Bay-09867 (hydrochloride)|||Ciprofloxacin HCl|||Ciprofloxacin hydrochloride
  • Ciprofloxacin-HCl in Methanol
  • C11668500 Ciprofloxacin hydrochloride
  • Ciprofloxacin hydrochloride
  • Ciprofloxacin (CPX) hydrochloride
  • Ciprofloxacin hydrochloride RS
  • Ciprofloxacin monohydrochloride (Standard)
  • CIPROFLOXACIN HCL
  • 93107-08-5
  • C17H19ClFN3O3xHCl
  • Pharmaceutical intermediate
  • 93107-08-5
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