Formoterol fumarate dihydrate
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- CAS-Nr.
- 183814-30-4
- Englisch Name:
- Formoterol fumarate dihydrate
- Synonyma:
- Formoterol fumarate dihydrate;Unii-W34shf8J2k;Formoterol fumarate dihydrate ,98.5%;Formoterol hemifumar;Fumarate Fumatrol Dihydrate;forMaMide fuMarate dihydrate;Formoterol Fumarate (100 mg);Formoterol fumarate 2-hydrate;Arformoterol Fumarate Dihydrate;Formoterol Hemifumarate Dihydrate
- CBNumber:
- CB02130563
- Summenformel:
- C23H28N2O8
- Molgewicht:
- 460.48
- MOL-Datei:
- 183814-30-4.mol
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Formoterol fumarate dihydrate Eigenschaften
- Schmelzpunkt:
- 116-120°C
- storage temp.
- 2-8°C
- Löslichkeit
- DMSO: soluble20mg/mL
- Aggregatzustand
- solid
- Farbe
- white to off-white
- InChIKey
- RATSWNOMCHFQGJ-XODSYJLDSA-N
- SMILES
- C(/C(=O)O)=C\C(=O)O.[C@@H](C1C=CC(O)=C(NC=O)C=1)(O)CN[C@@H](C)CC1C=CC(OC)=CC=1 |&1:8,22,r|
- CAS Datenbank
- 183814-30-4
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| RIDADR |
UN 2811 6.1 / PGII |
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| WGK Germany |
3 |
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| HS Code |
29242990 |
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| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications |
Acute Tox. 4 Inhalation
Aquatic Chronic 3
Repr. 2
STOT RE 2
STOT SE 1 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H332 |
Gesundheitsschädlich bei Einatmen. |
Akute Toxizität inhalativ |
Kategorie 4 |
Warnung |
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P261, P271, P304+P340, P312 |
| H370 |
Schädigt die Organe. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 1 |
Achtung |
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P260, P264, P270, P307+P311, P321,P405, P501 |
| H373 |
Kann die Organe schädigen bei längerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizität (wiederholte Exposition) |
Kategorie 2 |
Warnung |
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P260, P314, P501 |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
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Formoterol fumarate dihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale Yellow Solid
Biologische Aktivität
Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.
Arzneimittelwechselwirkung
The efficacy and tolerability of glycopyrronium/formoterol fumarate metered dose inhaler, a fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate 14.4/10 μg (equivalent to glycopyrrolate/formoterol fumarate 18/9.6 μg) delivered by metered dose inhaler using innovative co-suspension delivery technology, was investigated in patients (n = 292) with COPD [12C]. There were no meaningful pharmacokinetic interactions, whether drug–drug or due to formulation, between glycopyrronium and formoterol following treatment with formulated using a new co-suspension delivery technology. The incidence of cardiovascular events of special interest was low (stroke, 0%–0.4%; cardiac ischemia, 0.4%–2.3%; cardiac failure, 1.3%–2.5%; arrhythmia, 1.3%–3.2%), and no important trends in clinical laboratory results, vital signs, or electrocardiograms were observed[1].
Formoterol fumarate dihydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Formoterol fumarate dihydrate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 238)Lieferanten
183814-30-4()Verwandte Suche:
- Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, rel-, (2E)-2-butenedioate (2:1) (salt), dihydrate
- (±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate
- (r*,r*)-n-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate
- Formoterol fumarate dihydrate
- Formoterol Fumarate (100 mg)
- forMaMide fuMarate dihydrate
- N-(2-hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide fuMarate dihydrate
- Formoterol fumarate dihydrate, >=99%
- (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrateChemicalBook
- R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate
- Formoterol hemifumarate monohydrate
- Formoterol fumarate dihydrate Solution in Methanol, 100μg/mL
- Formoterol Fumarate Monohydrate/ dihydrate
- Formoterol hemifumar
- Formoterol fumarate dihydrateQ: What is
Formoterol fumarate dihydrate Q: What is the CAS Number of
Formoterol fumarate dihydrate Q: What is the storage condition of
Formoterol fumarate dihydrate
- Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate
- Formoterol fumarate 2-hydrate
- Formoterol hemifumarate
salt monohydrate
- Arformoterol Fumarate Dihydrate
- Formoterol Hemifumarate Dihydrate
- C13919000 FormoteroLfumaratEdihydrate
- FORMOTEROL FUMARATE DIHYDRATE USP
- Fumarate Fumatrol Dihydrate
- Formoterol fumarate dihydrate ,98.5%
- Unii-W34shf8J2k
- (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide
- 183814-30-4
- 183818-30-4
- C19H24N2O4189C4H4O4
- C23H32N2O10
- C42H52N4O122H2O
- Other APIs
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