Formoterol fumarate dihydrate
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Formoterol fumarate dihydrate 속성
- 녹는점
- 116-120°C
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 가용성20mg/mL
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- InChIKey
- RATSWNOMCHFQGJ-XODSYJLDSA-N
- SMILES
- C(/C(=O)O)=C\C(=O)O.[C@@H](C1C=CC(O)=C(NC=O)C=1)(O)CN[C@@H](C)CC1C=CC(OC)=CC=1 |&1:8,22,r|
- CAS 데이터베이스
- 183814-30-4
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 유엔번호(UN No.) | UN 2811 6.1 / PGII | ||
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| WGK 독일 | 3 | ||
| HS 번호 | 29242990 | ||
| 스토리지 클래스 | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications | Acute Tox. 4 Inhalation Aquatic Chronic 3 Repr. 2 STOT RE 2 STOT SE 1 |
| 그림문자(GHS): |
 
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| 신호 어: | Danger | |||||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Formoterol fumarate dihydrate C화학적 특성, 용도, 생산
화학적 성질
Pale Yellow Solid생물학적 활성
Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.Drug interactions
The efficacy and tolerability of glycopyrronium/formoterol fumarate metered dose inhaler, a fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate 14.4/10 μg (equivalent to glycopyrrolate/formoterol fumarate 18/9.6 μg) delivered by metered dose inhaler using innovative co-suspension delivery technology, was investigated in patients (n = 292) with COPD [12C]. There were no meaningful pharmacokinetic interactions, whether drug–drug or due to formulation, between glycopyrronium and formoterol following treatment with formulated using a new co-suspension delivery technology. The incidence of cardiovascular events of special interest was low (stroke, 0%–0.4%; cardiac ischemia, 0.4%–2.3%; cardiac failure, 1.3%–2.5%; arrhythmia, 1.3%–3.2%), and no important trends in clinical laboratory results, vital signs, or electrocardiograms were observed[1].Formoterol fumarate dihydrate 준비 용품 및 원자재
원자재
준비 용품
Formoterol fumarate dihydrate 공급 업체
글로벌( 238)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shandong Risen-Sun Pharmaceutical Co., Ltd. | +86-0538-8923092 13958575904 |
risensun-sales@jewim.com.cn | China | 43 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 |
3bsc@sina.com | China | 15813 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32273 | 50 |
| Syntechem Co.,Ltd | |
info@syntechem.com | China | 12973 | 57 |
| T&W GROUP | 021-61551611 13296011611 |
contact@trustwe.com | China | 9884 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 |
China | 9874 | 58 | |
| Simagchem Corp. | 86 592 2680277 |
sale@simagchem.com | China | 430 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 |
anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4773 | 55 |