Imidapril Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Imidapril is a new ACE inhibitor launched in Japan as a once-daily therapy for
hypertension. Its active metabolite has more potent inhibitory effects on all tissue ACES from
spontaneously hypertensive rats (SHRs) and Wistar Kyoto rats (WKYs) than many other ACE
inhibitors including enalapril and captopril. It has a very long duration of action. In strokeprone
spontaneously hypertensive rats (SHRSP), imidapril is effective in stroke prevention at
a considerably lower dose than enalapril. This stroke preventive effect has been suggested to
be primarily by an indirect mechanism related to the amelioration of kidney dysfunction.
Chemische Eigenschaften
White Solid
Verwenden
Angiotensin converting enzyme (ACE) inhibitor. Antihypertensive
Imidapril Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
