Benzimidazol
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- CAS-Nr.
- 51-17-2
- Bezeichnung:
- Benzimidazol
- Englisch Name:
- Benzimidazole
- Synonyma:
- 1H-BENZO[D]IMIDAZOLE;1H-BENZIMIDAZOLE;Benzimidazol;Benzoimidazole;BZI;Benzoglyoxaline;1H-Benzoimidazole;3-Azaindole;Benziminazole;TIMTEC-BB SBB004294
- CBNumber:
- CB2177003
- Summenformel:
- C7H6N2
- Molgewicht:
- 118.14
- MOL-Datei:
- 51-17-2.mol
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Benzimidazol Eigenschaften
- Schmelzpunkt:
- 169-171 °C (lit.)
- Siedepunkt:
- 360 °C
- Dichte
- 1.1151 (rough estimate)
- Brechungsindex
- 1.5500 (estimate)
- Flammpunkt:
- 360°C
- storage temp.
- Store below +30°C.
- Löslichkeit
- xylene: soluble1g in 2g (boiling)(lit.)
- Aggregatzustand
- Crystalline Powder or Crystals
- pka
- 5.532(at 25℃)
- Farbe
- Beige to brown
- Wasserlöslichkeit
- sparingly soluble
- maximale Wellenlänge (λmax)
- 271nm(MeOH)(lit.)
- Merck
- 14,1081
- BRN
- 109682
- Henry's Law Constant
- 2.7×101 mol/(m3Pa) at 25℃, HSDB (2015)
- Stabilität:
- Stable. Combustible. Incompatible with strong oxidising agents.
- InChI
- 1S/C7H6N2/c1-2-4-7-6(3-1)8-5-9-7/h1-5H,(H,8,9)
- InChIKey
- HYZJCKYKOHLVJF-UHFFFAOYSA-N
- SMILES
- c1ccc2[nH]cnc2c1
- LogP
- 1.320
- CAS Datenbank
- 51-17-2(CAS DataBase Reference)
- NIST chemische Informationen
- 1H-Benzimidazole(51-17-2)
- EPA chemische Informationen
- Benzimidazole (51-17-2)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi |
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| R-Sätze: |
36/37/38 |
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| S-Sätze: |
37/39-26-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
DD5425000 |
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| Hazard Note |
Irritant |
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| TSCA |
TSCA listed |
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| HS Code |
29339990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Giftige Stoffe Daten |
51-17-2(Hazardous Substances Data) |
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| Toxizität |
LD50 oral in mouse: 2910mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Benzimidazol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Benzimidazole is a sheet-like white crystal, with a temperature of 170 ℃, soluble in water and ethanol. Usually used as template compound in the preparation of molecularly imprinted polymer via electropolymerization and electrodeposition of pyrrole on a pencil graphite electrode,and also used in the preparation of benzimidazolium surfactant, 1-hexadecyl-1H-benzimidazole.
Allgemeine Beschreibung
White tabular crystals.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
An amine. Neutralizes acids to form salts plus water. These acid-base reactions are exothermic. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. May be shock sensitive.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Benzimidazole emits highly toxic fumes.
Brandgefahr
Flash point data for Benzimidazole are not available. Benzimidazole is probably combustible.
Pharmakologie
The mode of action of benzimidazoles has been described
in several comprehensive reviews (1,32,33). The primary
mode of action of benzimidazoles has been identified as
the specific binding to the β-subunit of fungal tubulin and,
consequently, an interference with microtubule assembly.
Microtubules are major components of the fungal
cytoskeleton and are involved in meiosis and mitosis, both
of which are blocked in the presence of benzimidazoles.
Sicherheitsprofil
Poison by intravenous
and intraperitoneal routes. Moderately toxic
by ingestion. Mutation data reported. When
heated to decomposition it emits highly
toxic fumes of NOx.
läuterung methode
It crystallises from water or aqueous EtOH (charcoal) and is dried at 100o for 12hours. [Beilstein 23 H 131, 23/6 V 196.]
Benzimidazol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Benzimidazol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 753)Lieferanten
51-17-2(Benzimidazol)Verwandte Suche:
- N,N'-O-PHENYLENEFORMAMIDINE
- 1,3-BENZODIAZOLE
- AKOS BBS-00004349
- BENZIMIDAZOLE
- 1,3-Diazaindene
- BENZIMIDAZOLE extrapure
- Azindol
- N,N'-Methylenyl-o-phenylenediamine
- BenziMidazole, 98% 100GR
- BenziMedazole
- Benzene and iMidazole
- Rabeprazole Impurity 28
- BenziMidazole, CP,98.0%
- AKOS BBS-0
- 2-MERCAPTO-5-(1-PYRROLY) BENZIMIDAZOLE
- 3-Azaindole
- Azindole
- Benziminazole
- BZI
- n,n’-methenyl-o-phenylenediamine
- N,N'-Methenyl-o-Phenylenediamine
- NSC 759
- nsc759
- o-Benzimidazole
- 1H-Benzimidazole(9CI)
- BENZIMIDAZOLE 99+%
- Benzimidazole,>98%
- BenzimidazoleForSynthesis
- Benzimidazole99%Min
- BenzoicAcidExtraPure
- 1H-Benzimidazole 98%
- Rabeprazole-5
- Benzimidazole >
- Benzimidazole, 99%, reagent grade
- Rabeprazole Impurity 34
- Rabeprazole Impurity 18
- BENZIMIDAZOLE FOR SYNTHESIS 100 G
- BENZIMIDAZOLE FOR SYNTHESIS 500 G
- Rabeprazole EP Impurity 1
- Diquafosol Impurity J
- Benzimidazole (6CI, 8CI)
- Rabeprazole Impurity 18（Diquafosol Impurity J）
- Compound PDK0248
- Benzimidazole 99% For Synthesis
- Rabeprazole Impurity 42
- 1H-Benzoimidazole
- 1H-BENZIMIDAZOLE
- 1H-BENZO[D]IMIDAZOLE
- Benzimidazol
- Benzoglyoxaline
- Benzoimidazole
- TIMTEC-BB SBB004294
- 51-17-2
- 517-17-2
- Heterocyclic Building Blocks
- Benzimidazoles
- Building Blocks
- BENZIMIDAZOLE
