(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid
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- CAS-Nr.
- 30484-77-6
- Bezeichnung:
- (E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid
- Englisch Name:
- Flunarizine dihydrochloride
- Synonyma:
- FLUNARIZINE HYDROCHLORIDE;FLUNARIZINE HCL;Gradient;FLUNARIZINE 2HCL;Flunarizine dihydrochloride CRS;Flunarizine Dihydrochloride (EP/BP);Issium;Mondus;r14950;Flunarl
- CBNumber:
- CB2377940
- Summenformel:
- C26H28Cl2F2N2
- Molgewicht:
- 477.42
- MOL-Datei:
- 30484-77-6.mol
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(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Eigenschaften
- Schmelzpunkt:
- 188-190C
- storage temp.
- 2-8°C
- Löslichkeit
- chloroform/methanol (9:1): 50 mg/mL, clear, colorless
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Merck
- 13,4170
- BRN
- 4284243
- InChI
- InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
- InChIKey
- RXKMOPXNWTYEHI-RDRKJGRWSA-N
- SMILES
- C(C1C=CC(F)=CC=1)(C1=CC=C(F)C=C1)N1CCN(C/C=C/C2C=CC=CC=2)CC1.Cl.Cl
- CAS Datenbank
- 30484-77-6(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
TK9187000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
Chemische Eigenschaften
White Solid
Verwenden
Flunarizine dihydrochloride has been used to study the effect of flunarizine on epileptiform activity. It is also used to study its effect on high-potassium induced increase of intracellular free calcium.
Allgemeine Beschreibung
Flunarizine has antihistamine, anticonvulsant and vestibular depressive properties. It protects endothelial cells from calcium overload-induced damage. Flunarizine is used to treat epilepsy, migraine prophylaxis, cerebral blood flow disturbances, peripheral vascular disease and vertigo.
Biologische Aktivität
Dual Na + /Ca 2+ channel blocker; a cerebral and peripheral vasodilator. Neuroprotective.
(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 432)Lieferanten
30484-77-6((E)-1-[Bis(4-fluorphenyl)methyl]-4-cinnamylpiperazindihydrochlorid)Verwandte Suche:
- Flugeral
- Flunarl
- Fluxarten
- Gradient
- Issium
- Flunarizine dihydrochloride,1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
- Flunarizine-d8 dihydrochloride
- 1-[Bis(4-fluorophenyl)Methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine Hydrochloride
- Dinaplex
- Flunagen
- Mondus
- Piperazine,1-[bis(4-fluorophenyl)Methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride(1:2)
- 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-piperazine,hydrochloride (1:2)
- (e)-1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)piperazinedihydroch
- 1-(BIS[4-FLUOROPHENYL]) DIHYDROCHLORIDE
- 1-[BIS(4-FLUOROPHENYL)METHYL]-4-(3-PHENYL-2-PROPENYL)PIPERAZINE 2 HCL
- 1-[BIS(4-FLUOROPHENYL)METHYL]-4-(3-PHENYL-2-PROPENYL)-PIPERAZINE DIHYDROCHLO RIDE
- (e)-1-(bis(p-fluorophenyl)methyl)-4-cinnamylpiperazinedihydrochloride
- 1-(bis(p-fluorophenyl)methyl)-4-cinnamyl-,dihydrochloride,(e)-piperazin
- kw-3149
- r14950
- (E)-1-[BIS(4-FLUOROPHENYL)METHYL]-4-(3-PHENYL-2-PROPENYL)PIPERAZINE DIHYDROCHLORIDE
- FLUNARIZINE DIHYDROCHLORIDE
- Flunarizine, DiHCl
- (E)-1-[bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride
- FLUNARIZINE DIHYDROCHLORIDE CA2+/NA+ CHA NNEL ANTA
- FLUNARIZIN-DIHYDROCHLORIDE
- FLUNARIZINE HYDROCHLORIDE EPF(CRM STANDARD)
- 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine dihydrochloride
- Flunarizine dihydrochloride CRS
- Flunarizine dihydrochloride for system suitability CRS
- Flunarizine dihydrochloride USP/EP/BP
- Flunarizine dihydrochloride for system suitability (Y0000266)
- 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine dihydrochloride
- FLURIZINE EP IMPURITY D
- Flunarizine dihydrochloride, 10 mM in DMSO
- Flunarizine for system suitability
- Flunarizine dihydrochloride - Bio-X ?
- Flunarizine Dihydrochloride 1.0 mg/ml in Methanol (as free base)
- D8-Flunarizine Dihydrochloride
- Flunarizine Dihydrochloride (EP/BP)
- FLUNARIZINE 2HCL
- FLUNARIZINE HCL
- FLUNARIZINE HYDROCHLORIDE
- 30484-77-6
- 30784-77-6
- 30848-77-6
- C26H26F2N22HCl
- C26H26F2N22ClH
- C26H28Cl2F2N2
- C26H28F2N2
- 47742
- Alphabetic
- FA - FL
- Voltage-gated Ion Channels
- BioChemical
- Cell Signaling and Neuroscience
- Calcium Channel Modulators
