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5'-DEOXYADENOSINE

5'-DEOXYADENOSINE Struktur
4754-39-6
CAS-Nr.
4754-39-6
Englisch Name:
5'-DEOXYADENOSINE
Synonyma:
5′-dAdo;5'-DEOXYADENOSINE;5’-deoxy-adenosin;5'-DEOXYADENOSINE;5''-DEOXYADENOSINE;Adenosine, 5'-deoxy-;5''-DEOXYADENOSINE, 10 mM in DMSO;2'-Deoxycytidine Monohydrate(2'-dC ? H?O);9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine;6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine
CBNumber:
CB5163003
Summenformel:
C10H13N5O3
Molgewicht:
251.24
MOL-Datei:
4754-39-6.mol
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5'-DEOXYADENOSINE Eigenschaften

Schmelzpunkt:
210-212 °C
Siedepunkt:
595.0±60.0 °C(Predicted)
Dichte
1.93±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml
Aggregatzustand
A crystalline solid
pka
13.29±0.70(Predicted)
Farbe
White to off-white
Biologische Quelle
synthetic (organic)
Wasserlöslichkeit
hot water: 19.60-20.40mg/mL, clear, colorless
InChI
InChI=1S/C10H13N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-4,6-7,10,16-17H,1H3,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChIKey
XGYIMTFOTBMPFP-KQYNXXCUSA-N
SMILES
C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1O

Sicherheit

WGK Germany  3
RTECS-Nr. AU7358650
Speicherklasse 11 - Combustible Solids

5'-DEOXYADENOSINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

5′-Deoxyadenosine has been used:
  • as a standard in mass spectroscopy
  • as an inhibitor for screening thymidine phosphorylase activity
  • as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay

Definition

ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.

Biochem/physiol Actions

5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.

5'-DEOXYADENOSINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

(S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosin

Downstream Produkte

5-Deoxy-D-ribose

5'-DEOXYADENOSINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 81)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Fuyang Ziyi Biological Pharmaceutical Co., Ltd. 19308655899; 19308655899
 2677609105@qq.com China 500 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833
 info@sagechem.com China 10265 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097
info@topbiochem.com China 9513 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860
 anhua.mao@aladdin-e.com China 29985 65
Hubei XinyuanShun Chemical Co., Ltd. 13971561712, 13995564702, 027-50664929
hbeixys2001@163.com China 3110 55
Bide Pharmatech Ltd. 400-164-7117 18317119277
 product02@bidepharm.com China 40000 60
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939
 shenlinxing@macklin.cn China 15775 55
Hangzhou J&H Chemical Co., Ltd. 0571-87396432
sales@jhechem.com China 14905 59
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51389 80
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105
 2881489226@qq.com China 89667 60

4754-39-6()Verwandte Suche:

N-Benzoyl-2'-desoxyadenosin N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-desoxyadenosin Adenosinnatrio-2',3'-phosphathydrat 2-Chloradenosinhemihydrat Adenosin-3',5'-phosphatmonohydrat Vidarabin Adenosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoate, Mononatriumsalz Adenosin-5'-(toluol-4-sulfonat) 2',3'-Isopropylidenadenosin Adenosin-3'-phosphatmonohydrat 8-Bromadenosin N,N-Dimethyladenosin 6-Benzylaminopurin 5'-Desoxy-5'-iodadenosin 5'-Acetyl-2',3'-isopropylenadenosin 2'-Desoxyadenosin-5'-(tetrahydrogentriphosphat) N-Benzoyl-2'-desoxyadenosin-3'-benzoat 8-Bromadenosin-2',3',5'-triacetat
  • 5’-deoxy-adenosin
  • (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol
  • 6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine
  • 9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine
  • Adenosine, 5'-deoxy-
  • 5′-dAdo
  • 2'-Deoxycytidine Monohydrate(2'-dC ? H?O)
  • 5'-Deoxyadenosine methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate
  • (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol
  • inhibit,5'DEOXYADENOSINE,5'-Deoxyadenosine,Endogenous Metabolite,Inhibitor,Orthopoxvirus,5' DEOXYADENOSINE
  • 5'-DEOXYADENOSINE
  • 5''-DEOXYADENOSINE
  • 5''-DEOXYADENOSINE, 10 mM in DMSO
  • 5'-DEOXYADENOSINE
  • 4754-39-6
  • BioChemical
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
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