5'-DEOXYADENOSINE
- CAS No.
- 4754-39-6
- Chemical Name:
- 5'-DEOXYADENOSINE
- Synonyms
- 5′-dAdo;5'-DEOXYADENOSINE;5’-deoxy-adenosin;5'-DEOXYADENOSINE;5''-DEOXYADENOSINE;Adenosine, 5'-deoxy-;5''-DEOXYADENOSINE, 10 mM in DMSO;2'-Deoxycytidine Monohydrate(2'-dC ? H?O);9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine;6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine
- CBNumber:
- CB5163003
- Molecular Formula:
- C10H13N5O3
- Molecular Weight:
- 251.24
- MDL Number:
- MFCD00056003
- MOL File:
- 4754-39-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 210-212 °C |
|---|---|
| Boiling point | 595.0±60.0 °C(Predicted) |
| Density | 1.93±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml |
| form | A crystalline solid |
| pka | 13.29±0.70(Predicted) |
| color | White to off-white |
| biological source | synthetic (organic) |
| Water Solubility | hot water: 19.60-20.40mg/mL, clear, colorless |
| InChI | InChI=1S/C10H13N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-4,6-7,10,16-17H,1H3,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1 |
| InChIKey | XGYIMTFOTBMPFP-KQYNXXCUSA-N |
| SMILES | C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1O |
| EWG's Food Scores | 1 |
| FDA UNII | 2U0TYC8Y5A |
| UNSPSC Code | 41106305 |
| NACRES | NA.51 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| RTECS | AU7358650 |
| Storage Class | 11 - Combustible Solids |
5'-DEOXYADENOSINE price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D1771 | 5′-Deoxyadenosine methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate | 4754-39-6 | 25mg | $307 | 2026-04-30 | Buy |
| Cayman Chemical | 29619 | 5''-Deoxyadenosine ≥95% | 4754-39-6 | 10mg | $44 | 2026-04-30 | Buy |
| Cayman Chemical | 29619 | 5''-Deoxyadenosine ≥95% | 4754-39-6 | 50mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 29619 | 5''-Deoxyadenosine ≥95% | 4754-39-6 | 100mg | $326 | 2026-04-30 | Buy |
| Cayman Chemical | 29619 | 5''-Deoxyadenosine ≥95% | 4754-39-6 | 250mg | $596 | 2026-04-30 | Buy |
5'-DEOXYADENOSINE Chemical Properties, Uses, Production
Description
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis.
Uses
5′-Deoxyadenosine has been used:
- as a standard in mass spectroscopy
- as an inhibitor for screening thymidine phosphorylase activity
- as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay
Definition
ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.
Biochem/physiol Actions
5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.
IC 50
Human Endogenous Metabolite
5'-DEOXYADENOSINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuyang Ziyi Biological Pharmaceutical Co., Ltd. | 19308655899; 19308655899 | 2677609105@qq.com | China | 500 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3110 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from 5'-DEOXYADENOSINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | 5'-Deoxyadenosine
4754-39-6
|
$1.00-22.00 | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-06-02 | 5'-DEOXYADENOSINE
4754-39-6
|
$31.00-85.00 | 99.85% | 10g | TargetMol Chemicals Inc. |
-
- 5'-Deoxyadenosine
4754-39-6
- $1.00-22.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5'-DEOXYADENOSINE
4754-39-6
- $31.00-85.00
- 99.85%
- TargetMol Chemicals Inc.
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