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Zavegepant

Zavegepant Struktur
1337918-83-8
CAS-Nr.
1337918-83-8
Englisch Name:
Zavegepant
Synonyma:
BHV-3500;Zavegepant;Vazegepant;Zevagepant;BMS 742413);Vazegepant free base;Zavegepant (Vazegepant;Zavegepant (BHV-3500, BMS-742413);N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide;(R)-N-(3-(7-Methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide
CBNumber:
CB75551430
Summenformel:
C36H46N8O3
Molgewicht:
638.8
MOL-Datei:
1337918-83-8.mol
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Zavegepant Eigenschaften

Siedepunkt:
933.7±65.0 °C(Predicted)
Dichte
1.285±0.06 g/cm3(Predicted)
pka
11.68±0.70(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
InChIKey
JJVAPHYEOZSKJZ-JGCGQSQUSA-N
SMILES
N1(C(N[C@H](CC2C=C(C)C3=C(C=2)C=NN3)C(N2CCN(C3CCN(C)CC3)CC2)=O)=O)CCC(C2=CC3=C(NC2=O)C=CC=C3)CC1

Sicherheit

Zavegepant Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Zavegepant, also known as Vazegepant, BHV-3500 and BMS 742413, is a highly potent, selective and structurally unique small molecule CGRP receptor antagonist. Vazegepant is the first and only CGRP receptor antagonist for intranasal administration currently in development for the acute treatment of migraine.

Nebenwirkungen

Zavegepant is generally well tolerated with side effects of dysgeusia, nausea, vomiting, and nasal discomfort that are generally transient and mild-to-moderate in severity.

Zavegepant Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Zavegepant Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 68)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985
Amyjiyunzen@yeah.net China 663 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317
 jiuyitime@fdachem.com China 9029 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830
 figo.gao@foxmail.com China 8497 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49975 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5743 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750
 info@finetechnology-ind.com China 9629 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471
sales@sarms4muscle.com China 10473 58
Chemtour Biotech Co., Ltd 		+8617327281506
 market@chemtour.com China 1521 58
R&D Scientific Inc. 		+1-2266000236
sales@rdscientific.com Canada 1864 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58
  • 1-Piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-N-[(1R)-1-[(7-methyl-1H-indazol-5-yl)methyl]-2-[4-(1-methyl-4-piperidinyl)-1-piperazinyl]-2-oxoethyl]-
  • Vazegepant free base
  • BHV-3500
  • Vazegepant
  • Zavegepant
  • Zavegepant (BHV-3500, BMS-742413)
  • Zevagepant
  • Zavegepant (Vazegepant
  • BMS 742413)
  • (R)-N-(3-(7-Methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide
  • N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide
  • N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4-(2-oxo-1H-quinolin-3-yl)piperidine-1-carboxamide
  • 1337918-83-8
  • API
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