Elamipretide

Elamipretide Struktur
736992-21-5
CAS-Nr.
736992-21-5
Englisch Name:
Elamipretide
Synonyma:
MTP-131;Centanafadine;SS-31, Elamipretide;Elamipretide acetate;RX-31;SS-31);Bendavia);Elamipretide;SS-31 10mg/20mg;ELAMIPRETIDE, >99%
CBNumber:
CB92708860
Summenformel:
C32H49N9O5
Molgewicht:
639.79
MOL-Datei:
736992-21-5.mol

Elamipretide Eigenschaften

Dichte
1.34±0.1 g/cm3(Predicted)
Löslichkeit
Methanol (Slightly), Water (Slightly)
pka
10.10±0.25(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Sequenz
H-d-Arg-dimethylTyr-Lys-Phe-NH2
Stabilität:
Hygroscopic
InChIKey
SFVLTCAESLKEHH-WKAQUBQDSA-N
SMILES
C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N

Sicherheit

Elamipretide Chemische Eigenschaften,Einsatz,Produktion Methoden

Mechanism of action

Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.

Clinical Use

Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.

Nebenwirkungen

Side effects of elamipretide include:
Mild redness or itching at the injection site
Headache
Dizziness

Elamipretide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Elamipretide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 181)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Kebeilai Pharmaceutical Biotech Co., Ltd.
+86-18240866958
wangjasmine7289@gmail.com China 1022 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+86-15350851019; +8615350851019
admin@86-ss.com China 999 58
Shandong Huizhihan Supply Chain Co., Ltd
+86-13363081709 +86-13363000288
3957328362@qq.com China 300 58
American HealthyMorph LLC
+85269498027
nancyyuan133@163.com China 169 58
Wuhan Haorong Biotechnology Co.,ltd
+8618565342920
sales@chembj.net China 300 58
Wuhan Kejiefeng Trading Co.,Ltd
+undefined18827003015
dong19981022@gmail.com China 178 58
Hebei Jiafan Trading Company Limited
+86-15354498258
sales01@jiafan88.com China 180 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-17392712697
1022@dideu.com China 3995 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533
Brad@rongnabiotech.com China 3390 58

736992-21-5()Verwandte Suche:


  • D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide
  • Elamipretide
  • Centanafadine
  • L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-
  • Elamipretide (TFA salt)
  • SS-31;MTP-131;BENDAVIA
  • Bendavia)
  • Elamipretide (SS-31
  • MTP-131
  • ELAMIPRETIDE, >99%
  • Elamipretide,MTP-131,RX-31,SS-31, >99%
  • Elamipretide (MTP-131
  • ELAMIPRETIDE (MTP-131;RX-31;SS-31)
  • RX-31
  • SS-31)
  • SS-31, Elamipretide
  • Elamipretide acetate
  • Elamipretide (SS-31) acetate
  • (S)-6-Amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide
  • Elamipretide(HY-P0125
  • Elamipretide、SS-31、H2N-D-Arg-Dmt-Lys-Phe-NH2
  • SS-31 10mg/20mg
  • Elamipretide (MTP-131, SS-31)
  • Elamipretide (MTP-131) ,S9803
  • 736992-21-5
  • 736992-21-5
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