Isoflupredon-21-acetat
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- CAS-Nr.
- 338-98-7
- Bezeichnung:
- Isoflupredon-21-acetat
- Englisch Name:
- Isoflupredone Acetate
- Synonyma:
- predef;U-6013;biorinil;NSC 12600;NSC 37977;Predef R 2X;IsoflupredineAcetate;21-Acetoxy-9-fluoro-;Isoflupredone acetate;Nintedanib Impurity 156
- CBNumber:
- CB9500538
- Summenformel:
- C23H29FO6
- Molgewicht:
- 420.47
- MOL-Datei:
- 338-98-7.mol
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Isoflupredon-21-acetat Eigenschaften
- Schmelzpunkt:
- 244-246° (dec)
- alpha
- D23 +108° (c = 0.735 in dioxane)
- Siedepunkt:
- 576.5±50.0 °C(Predicted)
- Dichte
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- Löslichkeit
- Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 12.05±0.70(Predicted)
- Farbe
- White to Off-White
- InChIKey
- ZOCUOMKMBMEYQV-BZIJPSHGNA-N
- SMILES
- [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@]1(C)[C@@](CC[C@@]21[H])(O)C(=O)COC(=O)C |&1:0,10,12,14,17,19,22,r|
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H361 |
Kann vermutlich die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen. |
Reproduktionstoxizität |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P281 |
Vorgeschriebene persönliche Schutzausrüstung verwenden. |
| P308+P313 |
BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Isoflupredon-21-acetat Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.
Veterinary Drugs and Treatments
Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids
can be used for its antiinflammatory or immunosuppressive
effects. Labeled indications for isoflupredone include: adjunctive
treatment of bovine ketosis, alleviating pain and lameness
associated with musculoskeletal conditions, acute hypersensitivity
reactions, adjunctive treatment of overwhelming infections with
severe toxicity, shock, supportive therapy in the treatment of stress
conditions (e.g., surgery), dystocia, retained placenta, inflammatory
ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce
inflammation associated with recurrent airway obstruction (RAO,
“heaves”, COPD).
While the drug could be used in small animals, it is recommended
to use other glucocorticoid agents instead, where there has been
more experience and other approved products for dogs and cats are
available.
Isoflupredon-21-acetat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Isoflupredon-21-acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 119)Lieferanten
338-98-7(Isoflupredon-21-acetat)Verwandte Suche:
9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17-valerat
Fluocinonid
Flumetason-21-pivalat
6α,9-Difluor-11β-hydroxy-16α,17-[isopropylidenbis(oxy)]pregna-1,4-dien-3,20-dion-21-propionat
Ciprocinonid
Triamcinolon-16-α,21-di(acetat)
Isoflupredon-21-acetat
Dexamethason-21-acetat
6α,9-Difluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-21-acetat
Amcinonid
Difluprednat
Diflorasondi(acetat)
Prednisolon
Isoflupredon
Prednison-21-acetat
Meprednison
Prednison
Prednisolon-21-acetat
- 4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-pregna-(11-be
- 4-diene-3,20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregna-21-acetate
- 9-alpha-fluoroprednisoloneacetate
- 9-fluoroprednisoloneacetate
- 9-fluorprednisoloneacetate
- biorinil
- predef
- ISOFLUPREDONE ACETATE (200 MG)
- isoflupredone 21-acetate
- 21-Acetoxy-9-fluoro-11,B-17-dihydroxy-pregna-1,4-diene-3,20-dione
- IsoflupredineAcetate
- 21-ACETOXY-9-FLUORO-11BETA,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11.beta.)-
- 21-acetoxy-9-fluoro-11,17-dihydroxy-pregna-1,4-diene-3,20-dione
- Isoflupredone acetate
- 21-ACETOXY-9-FLUORO-11SS,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE
- 21-(Acetyloxy)-9α-fluoro-11β,17α-dihyroxypregna-1,4-diene-3,20-dione
- U-6013
- 21-Acetoxy-9-fluoro-
- 9-Fluoroprednisolone-21-acetate
- NSC 12600
- NSC 37977
- Predef R 2X
- 2-((8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-diMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
- Isoflupredone Acetate USP
- 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β)-
- Isoflupredone Acetate USP/EP/BP
- Isoflupredone Acetate (1348907)
- Isofluprednisone acetate
- 9-Fluoroprednisolone acetate(Isoflupredone acetate)
- 21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-dienen-3,20-dione
- 1, 4-PREGNADIEN-9α-FLUORO-11β, 17, 21-TRIOL-3, 20-DIONE 21-ACETATE
- Nintedanib Impurity 156
- Isoflupredone Acetate, 10 mM in DMSO
- 9-fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate
- Prednisolone Acetate Impurity 6
- 2-((8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate (Prednisolone impurity)
- 338-98-7
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
