ChemicalBook >> CAS DataBase List >>Perfluorooctanoic Acid

Perfluorooctanoic Acid

CAS No.
335-67-1
Chemical Name:
Perfluorooctanoic Acid
Synonyms
Pfoa;PERFLUOROOCTANOIC ACID;PERFLUOROOCTANOATE;PERFLUORO-N-OCTANOIC ACID;N-PERFLUOROOCTANOIC ACID;Perfluoroctanoic acid;PERFLUOROCAPRYLIC ACID;Perfluorooctanoic acid(PFOA);2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-PENTADECAFLUOROOCTANOIC ACID;A 5717
CBNumber:
CB00128256
Molecular Formula:
C8HF15O2
Molecular Weight:
414.07
MDL Number:
MFCD00004174
MOL File:
335-67-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-20 17:44:43

Perfluorooctanoic Acid Properties

Melting point 55-56 °C (lit.)
Boiling point 189 °C/736 mmHg (lit.)
Density 1,7 g/cm3
Flash point 189-192°C
storage temp. 2-8°C
solubility 3.4g/l
form Crystalline Powder
pka 0.50±0.10(Predicted)
Specific Gravity 1.7
color White
PH 2.6 (1g/l, H2O, 20℃)
Water Solubility 3.4 g/L
BRN 1809678
Henry's Law Constant 4.9×10-2 mol/(m3Pa) at 25℃, Kutsuna and Hori (2008)
Stability Stable. Incompatible with bases, oxidizing agents, reducing agents.
Major Application PFAS testing
cleaning products
cosmetics
environmental
food and beverages
personal care
InChI 1S/C8HF15O2/c9-2(10,1(24)25)3(11,12)4(13,14)5(15,16)6(17,18)7(19,20)8(21,22)23/h(H,24,25)
InChIKey SNGREZUHAYWORS-UHFFFAOYSA-N
SMILES OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Toxicology and Carcinogenesis Toxicology and Carcinogenesis Studies of Perfluorooctanoic Acid (CASRN 335-67-1) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley SD) Rats (Revised)
Substances of Very High Concern (SVHC) Candidate List Pentadecafluorooctanoic acid (PFOA) (335-67-1)
CAS DataBase Reference 335-67-1(CAS DataBase Reference)
EWG's Food Scores 8
FDA UNII 947VD76D3L
Proposition 65 List Perfluorooctanoic Acid (PFOA)
IARC 2B (Vol. 110) 2017
NIST Chemistry Reference Octanoic acid, pentadecafluoro-(335-67-1)
EPA Substance Registry System Perfluorooctanoic acid (335-67-1)
Toxicological Profile|ATSDR Pentadecafluorooctanoic acid|Toxicological Profile|ATSDR
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H302+H332-H318-H351-H360D-H362-H372
Precautionary statements  P260-P263-P280-P304+P340+P312-P305+P351+P338-P308+P313
target organs Eyes,Central nervous system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  C,Xi,T,F
Risk Statements  22-34-52/53-39/23/24/25-23/24/25-11
Safety Statements  26-36/37/39-45-36/37-16-7
RIDADR  UN 3261 8/PG 3
WGK Germany  2
RTECS  RH0781000
Hazard Note  Corrosive
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29159080
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
Hazardous Substances Data 335-67-1(Hazardous Substances Data)
Toxicity dnd-esc 50 mmol MUREAV 89,95,81
NFPA 704
1
3 0

Perfluorooctanoic Acid price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 171468 Perfluorooctanoic acid 96% 335-67-1 5g $47.8 2026-04-30 Buy
Sigma-Aldrich 171468 Perfluorooctanoic acid 96% 335-67-1 25g $158 2026-04-30 Buy
TCI Chemical A5717 Pentadecafluorooctanoic Acid (ca. 5mmol)[Ion-Pair Reagent for LC-MS] >98.0%(T) 335-67-1 1sample $77 2023-06-20 Buy
TCI Chemical A5720 Pentadecafluorooctanoic Acid High Grade [Ion-Pair Reagent for LC-MS] >98.0%(T) 335-67-1 1g $76 2021-12-16 Buy
Cayman Chemical 37232 Pentadecafluorooctanoic Acid 335-67-1 5g $44 2026-04-30 Buy
Product number Packaging Price Buy
171468 5g $47.8 Buy
171468 25g $158 Buy
A5717 1sample $77 Buy
A5720 1g $76 Buy
37232 5g $44 Buy

Perfluorooctanoic Acid Chemical Properties, Uses, Production

Description

Perfluorooctanoic Acid (PFOA) is a synthetic perfluorinated chemical and a by-product of the production of fluoropolymers. Perfluorinated chemicals (PFCs) are a group of organics used in the manufacture of fluoropolymer coatings and products that are resistant to heat, oil, stains, grease and water.

Uses

Perfluorooctanoic Acid (PFOA) is used as a surfactant in the emulsion polymerisation of fluoropolymers for the manufacture of products such as Teflon and Gore-Tex. PFOA is particularly used in the manufacture of PTFE. However, manufacturers are now using a new process that does not require this chemical.

Definition

ChEBI: Perfluorooctanoic acid is a fluoroalkanoic acid that is perfluorinated octanoic acid. It has a role as an environmental contaminant, a xenobiotic, a carcinogenic agent, a surfactant and an endocrine disruptor. It is functionally related to a perfluorooctane and an octanoic acid.

Hazard

Perfluorooctanoic Acid (PFOA) persists in the environment and does not break down. It is toxic and carcinogenic to animals. In vivo studies have found that exposure to PFOA increases the risk of certain tumours of the liver, testes, mammary gland (breast) and pancreas. The substance is irritating to the eyes, skin and respiratory tract. May be carcinogenic to humans. May cause toxicity to human reproduction or development. PFOA has been detected in the blood of more than 98% of the general U.S. population at levels in the low and parts per billion range, with higher levels in chemical plant employees and surrounding subpopulations. Exposure has been associated with elevated cholesterol and uric acid levels, and elevated serum PFOA levels have recently been found to be associated with an increased risk of chronic kidney disease in the general U.S. population, consistent with earlier animal studies.

Global Suppliers ( 427)
Supplier Tel Email Country ProdList Advantage
Yangzhou modier Electronic Materials Co., Ltd 13761402923 19975033992 market@modeltemol.com China 7841 58
Shanghai Titan Scientific Co.,Ltd 18616708014 yhx@titansci.com China 9999 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65

View Latest Price from Perfluorooctanoic Acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Perfluorooctanoic acid pictures 2026-07-20 Perfluorooctanoic acid
335-67-1
$50.00-128.00 99.62% 10g TargetMol Chemicals Inc.
Perfluorooctanoic Acid pictures 2026-05-28 Perfluorooctanoic Acid
335-67-1
$80.00-100.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
PERFLUOROOCTANOIC ACID AMMONIUM SALT pictures 2021-10-19 PERFLUOROOCTANOIC ACID AMMONIUM SALT
3825-26-1
$10.00 1KG 99% 20 tons Hebei Zhanyao Biotechnology Co. Ltd
PENTADECAFLUOROOCTANOIC ACID PERFLUOROHEPTANE CARBOXYLIC ACID PERFLUOROCAPRYLIC ACID RARECHEM AL BO 0424 IPC-PFFA-8 IPC-PFFA-8 HG 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-PENTADECAFLUOROOCTANOIC ACID Fluorad FC-26 Hexanoyl fluoride, 3,3,4,4,5,5,6,6,6-nonafluoro-2-oxo- Octanoicacid,pentadecafluoro- Pentadecafluoro-1-octanoic acid Pentadecafluoro-n-octanoic acid pentadecafluoro-n-octanoicacid pentadecafluoro-octanoicaci JACS-335-67-1 Caprylic acid, fluorinated Octanoic acid, fluorinated Pentadecafluorooctanoic Acid Hydrate Pentadecafluorooctanoicacid,analyticalgrade Pentadecafluorooctanoicacid,min.98% pentadecafluorooctanoic acid high grade perfluorooctanoic acid high grade n-Perfluorooctanoic acid 95% Perfluorooctanoic acid 98% n-Perfluorooctanoicacid99% Pentadecafluorooctanoic acid, Perfluorocaprylic acid, Perfluorooctanoic acid Perfluorocaprylic acid solution, Perfluorooctanoic acid solution Eftop EF 201 Perfluorocaprylic acid, Perfluorooctanoic acid Pentadecafluorooctanoic acid, min. 98% Pentadecafluorooctanoic acid,96% Pentadecafluorooctanoic acid,PFOA, Perfluorocaprylic acid, Perfluorooctanoic acid Perfluorocaprylic acid 5g [335-67-1] Perfluorooctanoic acid,PFOA, Pentadecafluorooctanoic acid, Perfluorocaprylic acid, Perfluorooctanoic acid Pentadecafluorocaprylic acid Pentadecafluorooctanoic acid Solution PENTADECAFLUOROOCTANOIC ACID HIGH GRADE [ION-PAIR REAGENT FOR LC-MS] PENTADECAFLUOROOCTANOIC ACID (CA. 5MMOL) [ION-PAIR REAGENT FOR LC-MS] Perfluorocapylicacid Perfluoroctanoic acid perfluoroctanoicacid perfluoroctanylacid Petfluorooctanoicacid Fluorooctanoic acid Perfluorocaprylic acid, Pentadecafluorooctanoic acid Pentadecafluorooctanoic acid, 96% 25GR Pentadecafluorooctanoic acid, 96% 5GR A 5717 EF 201 NSC 95114 Perfluoro-1-heptanecarboxylic Acid Octanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluoro- IPC-PFFA-8 HG Perfluorooctanoic Acid High Grade IPC-PFFA-8 Perfluorooctanoic Acid Pentadecafluorooctan IPC-PFFA-8 (ca. 5mmol) PENTADECAFLUOROOCTANOIC ACID FOR SYNTHES Perfluorocaprylic acid Perfluorooctanoic acid IPC-PFFA-8 HG