ChemicalBook >> CAS DataBase List >>Edetate Disodium
Edetate Disodium
- CAS No.
- 139-33-3
- Chemical Name:
- Edetate Disodium
- Synonyms
- EDTA-2NA;DISODIUM EDTA;DISODIUM EDETATE;ETA;EDETATE DISODIUM;EDTA DISODIUM;EDTA DISODIUM SALT;TITRIPLEX III;DISODIUM ETHYLENEDIAMINETETRAACETATE;EDTA NA2
- CBNumber:
- CB00131104
- Molecular Formula:
- C10H14N2Na2O8
- Molecular Weight:
- 336.21
- MDL Number:
- MFCD00070672
- MOL File:
- 139-33-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-24 18:39:39
| Melting point | 248 °C (dec.)(lit.) |
|---|---|
| Boiling point | >100 °C |
| Density | 1.01 g/mL at 25 °C |
| vapor pressure | 0Pa at 25℃ |
| refractive index | n20/D 1.363 |
| storage temp. | 2-8°C |
| solubility | H2O: clear, colorless |
| form | solution |
| color | ≤5 (0.5 M)(APHA) |
| PH | 8.0±0.2 |
| Odor | at 100.00%. odorless |
| Water Solubility | Miscible with water. |
| BRN | 3822669 |
| Stability | Hygroscopic |
| Cosmetics Ingredients Functions |
CHELATING VISCOSITY CONTROLLING |
| Cosmetic Ingredient Review (CIR) | Ethylenediaminetetraacetic acid disodium salt (139-33-3) |
| InChI | 1S/C10H16N2O8.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+1/p-2 |
| InChIKey | ZGTMUACCHSMWAC-UHFFFAOYSA-L |
| SMILES | [Na+].[Na+].OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O |
| LogP | -4.3 at 25℃ |
| CAS DataBase Reference | 139-33-3(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | EDTA, DISODIUM |
| FDA 21 CFR | 175.105; 176.150; 176.170;177.1200; 178.1010; 178.3570 |
| EWG's Food Scores | 1 |
| FDA UNII | 8NLQ36F6MM |
| EPA Substance Registry System | Ethylenediaminetetraacetic acid disodium salt (139-33-3) |
| Cosmetics Info | Disodium EDTA |
| Absorption | cut-off at 268nm |
| UNSPSC Code | 12352107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H303-H332-H372-H412 | |||||||||
| Precautionary statements | P260-P271-P273-P304+P340+P312-P312-P501 | |||||||||
| Hazard Codes | Xn,C | |||||||||
| Risk Statements | 36/38-36/37/38-22-34-21/22 | |||||||||
| Safety Statements | 26-36-37/39-45-36/37/39-36/37 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | AH4410000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29224999 | |||||||||
| Storage Class | 12 - Non Combustible Liquids | |||||||||
| Hazardous Substances Data | 139-33-3(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,260mg/kg (260mg/kg),Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 126S, 1956. | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Edetate Disodium price More Price(80)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E7889 | Ethylenediaminetetraacetic acid disodium salt solution for molecular biology, 0.5 M in H2O, DNase, RNase, NICKase and protease, none detected | 139-33-3 | 100ml | $85.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | E7889 | Ethylenediaminetetraacetic acid disodium salt solution for molecular biology, 0.5?M in H2O, DNase, RNase, NICKase and protease, none detected | 139-33-3 | 1L | $423 | 2026-04-30 | Buy |
| Sigma-Aldrich | 4055-OP | Ethylenediaminetetraacetic acid disodium salt solution OmniPur? Grade | 100ml | $75.9 | 2026-04-30 | Buy | |
| Sigma-Aldrich | 4055-OP | Ethylenediaminetetraacetic acid disodium salt solution OmniPur? Grade | 500ml | $278 | 2026-04-30 | Buy | |
| Sigma-Aldrich | 2854 | Ethylenediaminetetraacetic acid disodium salt solution 2%, solution | 139-33-3 | 15ml | $95.2 | 2026-04-30 | Buy |
Edetate Disodium Chemical Properties, Uses, Production
Description
Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Application
Edetate disodium anhydrous is a polyvalent ion chelator that reduces blood concentrations of calcium or digitalis. It has a long duration of action as patients are generally given 1 daily dose. The therapeutic index is wide, as high doses are generally well tolerated. Patients should be counselled regarding the risk of postural hypotension, effects of myocardial contractility, hypokalemia, hypomagnesemia, and hypoglycemia.
Edetate Disodium Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 1064)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong Ru Tong Chemical Co., Ltd | 18962933129 18962933129 | 1031672739@qq.com | China | 18 | 58 |
| Guangzhou Yunmen Biotechnology Co., Ltd | 0751-18902340975/189023400307 18902340307 | 3356812514@qq.com | China | 9225 | 58 |
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| Shijiazhuang Ruitian Biochemical Co. Ltd | 15831127780 | 52714113@qq.com | China | 2355 | 58 |
| Shandong Zhongyuan Chemical Co., Ltd | 19812484234 19812484234 | 840301290@qq.com | China | 56 | 58 |
| Wuhan Jiyesheng Chemical Co., Ltd | 15307169873 | 1218603465@qq.com | China | 2158 | 58 |
| Wuhan Ji Ye Sheng Chemical Co., Ltd. | 15387013945 | 1806989108@qq.com | China | 2163 | 58 |
| Jinan Shengfeng Industry and Trade Co., Ltd | 186-15597515 17615809616 | 1249887377@qq.com | China | 204 | 58 |
| Shandong Zhuojindada New Materials Co., Ltd. | 16615776286 16615776286 | 16615776286@163.com | China | 535 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
Related articles
- Ethylenediaminetetraacetic Acid Disodium Salt: Antifungal Activity and Applications in Cellular Imaging
- Ethylenediaminetetraacetic acid disodium salt exhibits potent antifungal effects and aids in producing high-quality silicon na....
- May 28,2024
- Mechanism of EDTA
- Ethylenediaminetetraacetic acid disodium salt also known as disodium ethylenediamine tetraacetate, commonly known as disodium ....
- Mar 21,2022
- Ethylenediaminetetraacetic acid disodium salt
- Ethylenediaminetetraacetic acid disodium salt (EDTA) (CAS: 139-33-3) is a good compounding agent. It has six coordination atom....
- Nov 10,2021
Related Questions
Ask a questionQ:Why is disodium EDTA added to cosmetics?jennie - Apr 17,2026
A:Disodium EDTA, also known as Ethylenediaminetetraacetic acid disodium salt, is a high-performance metal ion chelating agent and a common additive in cosmetic formulations. It precisely captures and binds to metal ions such as calcium, magnesium, copper, and iron introduced into water and raw materials, preventing these ions from causing oxidation, discoloration, or turbidity in skincare and makeup products. Simultaneously, it enhances the effectiveness of preservative systems, reduces the risk of product spoilage, makes cosmetics more stable and durable, extends their shelf life, and is gentle and safe for the skin when added in compliant amounts, without causing irritation to normal skin.
View Latest Price from Edetate Disodium manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | Disodium edetate dihydrate
6381-92-6
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2024-03-11 | Disodium edetate dihydrate
6381-92-6
|
$18.00-28.00 | 500kg | 99.9 | 200tons | Shandong Juchuang Chemical Co., LTD | |
 |
2023-12-20 | Disodium edetate dihydrate
6381-92-6
|
$1250.00 | 10ton | 99% | 5000ton | Hebei Dongdu Import and Export Co. LTD |
-
- Disodium edetate dihydrate
6381-92-6
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Disodium edetate dihydrate
6381-92-6
- $18.00-28.00
- 99.9
- Shandong Juchuang Chemical Co., LTD
-
- Disodium edetate dihydrate
6381-92-6
- $1250.00
- 99%
- Hebei Dongdu Import and Export Co. LTD
139-33-3 (Edetate Disodium) Related Search:
Tripotassium hydrogen ethylenediaminetetraacetate
Ethylenediaminetetraacetic acid tetrasodium salt
Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI)
Cytidine-5'-triphosphate disodium salt dihydrate
Sodium phosphate dibasic dodecahydrate
Ethylenediaminetetraacetic acid
Dipotassium EDTA
Disodium pamidronate
Fructose sodium diphosphate
Folic acid
1of5
SODIUM (DI) ETHYLENEDIAMINE TETRAACETATE DIHYDRATE
VERSENE NA, DIHYDRATE
VERSENE DISODIUM
WANKLYN'S EDTA
Ceftriaxone Impurity 21（EDTA Disodium）
disodium ethylenediamintetraacetate
EDTA two sodium
EDTA TITRANT 0.05M VOL SOL
EDTA disodium salt solution, 0.1000mol/L(0.1M)
EDTA disodium salt solution, 0.2000mol/L(0.2M)
EDTA disodium salt solution, 0.02000mol/L(0.02M)
EDTA disodium salt solution, 0.01000mol/L(0.01M)
Ethylenediaminetetraacetic acid disodium salt(EDTA)
TITRAVER(R) HARDNESS REAGENT
TITRIPLEX(R) III
(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, Ethylenediaminetetraacetic acid solution disodium salt, Ethylenediaminetetraacetic acid disodium salt standard solution
IDRANAL(R) III standard solution
IDRANAL(R) III concentrate
(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, Ethylenediaminetetraacetic acid solution disodium salt
Ethylenediamine-tetraacetic acid disodium salt concentrate
(Ethylenedinitrilo)tetraacetic acid disodium salt, Additive Screening Solution 43/Fluka kit no 78374, EDTA disodium salt
Disotate
Ethylenediaminetetraacetic acid, disodium salt, dnase, rnase and protease free, for
Ethylenediaminetetraacetic acid, disodium salt, DNAse, RNAse and Protease free, for molecular biology
Ethylenediaminetetraacetic Acid Disodium Salt Solution [for Determination of water hardness] [for ppm]
(Ethylenebisnitrilo)tetraacetic acid 1,1''-disodium salt
Ethylenedinitrilotetraacetic acid dihydrogen 1,1''-disodium salt
N,N'-Disodium dihydrogen ethylenediamine-N,N,N',N'-tetraacetate
Ethylenediamine Tetraacetic Acid, Disodium Salt, Standard Solution, 0.1M
EDTA Titrant, 0.1 Molar (M/10) Volumetric Solution
EDTA disodium salt (anhydrous)
(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt
Ethylenediaminetetraacetic acid solution disodium salt
Ethylenediaminetetraacetic acid, disodium salt,99+%,for molecular biology,DNAse, RNAse and
Ethylenediaminetetraacetic Acid Disodium Salt Solution [for ppm]
Ethylenediaminetetraacetic Acid Disodium Salt Solution, for D.H. [determination of Water-hardness]
Ethylenediamine tetra acetic acid two sodium (EDTA two sodium)
Ethylenediamine tetra acetic acid two sodium salt
Ethylenediamine tetra acetic acid two sodium magnesium solution
Ethylenedinitrilotetraacetic acid disodium salt, 99%, for molecular biology
hot sale EDTA 2Na with high quality
High quality CAS No.:139-33-3 EDTA
High purity CAS No.:139-33-3 EDTA CAS NO.139-33-3
(ethylenedinitrilo)tetra-aceticacidisodiumsalt
cheladrate
chelaplexiii
chelatoniii
complexoniii
dinatriumethylendiamintetraacetat
disodium(ethylenedinitrilo)tetraacetate
disodium(ethylenedinitrilo)tetraaceticacid
disodiumdiacidethylenediaminetetraacetate
disodiumdihydrogen(ethylenedinitrilo)tetraacetate
disodiumedathamil
disodiumsaltofedta
disodiumsequestrene
disodiumtetracemate
disodiumversenate
