Ethyl 5-hydroxynicotinate
- CAS No.
- 59288-38-9
- Chemical Name:
- Ethyl 5-hydroxynicotinate
- Synonyms
- 3-(Ethoxycarbonyl)-5-hydroxypyridine;ethyl 5-hydroxynicotinate;ethyl 5-hydroxypyridine-3-carboxylate;Ethyl 5-hydroxy-3-pyridinecarboxylate;5-hydroxy-3-pyridinecarboxylic acid ethyl ester;5-Hydroxypyridine-3-carboxylic acid ethyl ester;3-Pyridinecarboxylic acid, 5-hydroxy-, ethyl ester;Ethyl 5-hydroxypyridine-3-carboxylate, 3-(Ethoxycarbonyl)-5-hydroxypyridine
- CBNumber:
- CB01010806
- Molecular Formula:
- C8H9NO3
- Molecular Weight:
- 167.16
- MDL Number:
- MFCD00510027
- MOL File:
- 59288-38-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 5-hydroxynicotinate 97% | OR51770 | 250mg | $21 |
| Ethyl 5-hydroxynicotinate 97% | OR51770 | 1g | $41 |
| Ethyl 5-hydroxynicotinate 97% | OR51770 | 5g | $157 |
| ethyl 5-hydroxypyridine-3-carboxylate | 189090 | 5.00g | $898 |
| ethyl 5-hydroxypyridine-3-carboxylate | 189090 | 10.00g | $1750 |
| More product size | |||
| Boiling point | 375.4±22.0 °C(Predicted) |
|---|---|
| Density | 1.233±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 8.48±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C8H9NO3/c1-2-12-8(11)6-3-7(10)5-9-4-6/h3-5,10H,2H2,1H3 |
| InChIKey | LFDNUOROKFFJLE-UHFFFAOYSA-N |
| SMILES | C1=NC=C(O)C=C1C(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314-H318 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-37/39 |
| HS Code | 29339900 |
Ethyl 5-hydroxynicotinate price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR51770 | Ethyl 5-hydroxynicotinate 97% | 59288-38-9 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR51770 | Ethyl 5-hydroxynicotinate 97% | 59288-38-9 | 1g | $41 | 2026-06-04 | Buy |
| Apolloscientific | OR51770 | Ethyl 5-hydroxynicotinate 97% | 59288-38-9 | 5g | $157 | 2026-06-04 | Buy |
| Matrix Scientific | 189090 | ethyl 5-hydroxypyridine-3-carboxylate | 59288-38-9 | 5.00g | $898 | 2026-05-18 | Buy |
| Matrix Scientific | 189090 | ethyl 5-hydroxypyridine-3-carboxylate | 59288-38-9 | 10.00g | $1750 | 2026-05-18 | Buy |
Ethyl 5-hydroxynicotinate Chemical Properties,Uses,Production
Chemical Properties
Off-white powder
Synthesis
27828-71-3
64-17-5
59288-38-9
Stage B: Synthesis of ethyl 5-hydroxynicotinate 1. 2.5 g (18 mmol) of 5-hydroxy-3-pyridinecarboxylic acid prepared in Stage A was dissolved in 50 mL of anhydrous ethanol, and the solution was cooled to 0 °C. 2. 4.4 mL (61 mmol) of thionyl chloride was added slowly dropwise with stirring, taking care to control the rate of dropwise acceleration to avoid violent exotherm. 3. After the dropwise addition, the reaction mixture was heated to reflux and kept for 24 hours. 4. After completion of the reaction, the solvent was removed by evaporation under reduced pressure to obtain the crude product. 5. The crude product was poured into an appropriate amount of ice water, stirred and filtered to collect the solid. 6. 2.5 g (yield: 83%) of ethyl 5-hydroxynicotinate was obtained after drying as a white powder. Product Characterization: - Molecular Formula: C8H9NO3 - Melting point: 150 ℃ - 1H NMR (300 MHz, DMSO-d6) δ (ppm): 8.74 (d, J = 1.2 Hz, 1H), 8.60 (d, J = 2.6 Hz, 1H), 8.07 (m, 1H), 4.44 (q, J = 7.1 Hz, 2H), 1.42 (t, J = 7.1 Hz, 3H) - IR (KBr, cm-1): 3044, 2874, 2677, 1731
References
[1] Patent: WO2006/103120, 2006, A2. Location in patent: Page/Page column 115-116
[2] Patent: CN105418620, 2016, A. Location in patent: Paragraph 0008; 0009
Ethyl 5-hydroxynicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13523716970 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from Ethyl 5-hydroxynicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-14 | Ethyl 5-hydroxynicotinate
59288-38-9
|
1kg | 99% | 5 tons | Shijiazhuang Dowell Chemical Co.,Ltd |
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- Ethyl 5-hydroxynicotinate
59288-38-9
- 99%
- Shijiazhuang Dowell Chemical Co.,Ltd
