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3-Fluoro-4-methoxyphenylacetic acid

CAS No.
452-14-2
Chemical Name:
3-Fluoro-4-methoxyphenylacetic acid
Synonyms
RARECHEM AL BO 1534;3F-4-METHOXYPHENYLESSIGSRE 5 G;4-(Carboxymethyl)-2-fluoroanisole;3-FLUORO-4-METHOXYPHENYLACETIC ACID;3-Fluoro-4-methyloxyphenylaceticacid;3-Fluoro-4-methoxyphenylaceticacid98%;Benzeneacetic acid, 3-fluoro-4-methoxy-;2-(3-fluoro-4-methoxyphenyl)acetic acid;3-Fluoro-4-methoxyphenylacetic acid 98%;4-(3-Fluoro-4-Methyloxyphenylacetic acid
CBNumber:
CB0104052
Molecular Formula:
C9H9FO3
Molecular Weight:
184.16
MDL Number:
MFCD00060353
MOL File:
452-14-2.mol
Last updated:2026-01-13 11:12:40
Product description Number Pack Size Price
3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) 8.43872 5G $61
3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) 8.43872 10g $149
3-Fluoro-4-methoxyphenylacetic acid F599325 250mg $45
3-Fluoro-4-methoxyphenylacetic acid J98090 5g $11
3-Fluoro-4-methoxyphenylacetic acid 98% PC3802 5g $15
More product size

3-Fluoro-4-methoxyphenylacetic acid Properties

Melting point 111-113°C
Boiling point 309.0±27.0 °C(Predicted)
Density 1.269±0.06 g/cm3(Predicted)
storage temp. Store below +30°C.
pka 4.25±0.10(Predicted)
form powder
color White to off-white
InChI 1S/C9H9FO3/c1-13-8-3-2-6(4-7(8)10)5-9(11)12/h2-4H,5H2,1H3,(H,11,12)/p-1
InChIKey VURNBRZIFABCRU-UHFFFAOYSA-M
SMILES Fc1c(ccc(c1)CC(=O)[O-])OC
CAS DataBase Reference 452-14-2(CAS DataBase Reference)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  WGK 1
HazardClass  IRRITANT
HS Code  2918290090
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Dam. 1

3-Fluoro-4-methoxyphenylacetic acid price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.43872 3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) 452-14-2 5G $61 2025-07-31 Buy
Sigma-Aldrich 8.43872 3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) 452-14-2 10g $149 2023-01-07 Buy
TRC F599325 3-Fluoro-4-methoxyphenylacetic acid 452-14-2 250mg $45 2021-12-16 Buy
AK Scientific J98090 3-Fluoro-4-methoxyphenylacetic acid 452-14-2 5g $11 2021-12-16 Buy
Apolloscientific PC3802 3-Fluoro-4-methoxyphenylacetic acid 98% 452-14-2 5g $15 2021-12-16 Buy
Product number Packaging Price Buy
8.43872 5G $61 Buy
8.43872 10g $149 Buy
F599325 250mg $45 Buy
J98090 5g $11 Buy
PC3802 5g $15 Buy

3-Fluoro-4-methoxyphenylacetic acid Chemical Properties,Uses,Production

Synthesis

3-fluoro-4-methoxyphenylacetonitrile (42 g, 0.25 mol) was heated for 5 h with 32 g of potassium hydroxide solution in 120 mL of ethanol and 30 mL of water. After the distillation of ethanol, the residue was diluted with water to a volume of 175 mL. The solution was filtered over the charcoal, and the filtrate was acidified by 50 percent H2SO4. The resulting solid was filtered and dried, yielding 3-Fluoro-4-methoxyphenylacetic acid.

References

[1] Collection of Czechoslovak Chemical Communications, 1990, vol. 55, # 1, p. 296 - 306
[2] European Journal of Medicinal Chemistry, 2014, vol. 87, p. 508 - 518
[3] Monatshefte fuer Chemie, 1955, vol. 86, p. 511,515
[4] DRP/DRBP Org.Chem.,
[5] Chemische Berichte, 1952, vol. 85, p. 577,580

404-90-0
452-14-2
Synthesis of 3-Fluoro-4-methoxyphenylacetic acid from 3-FLUORO-4-METHOXYPHENYLACETONITRILE
Global( 143)Suppliers
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Shaanxi Dideu Medichem Co. Ltd
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View Lastest Price from 3-Fluoro-4-methoxyphenylacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Fluoro-4-methoxyphenylacetic acid  pictures 2025-12-12 3-Fluoro-4-methoxyphenylacetic acid
452-14-2
US $55.00-15.00 / KG 1KG 99% 20000KG Shaanxi Dideu Medichem Co. Ltd
2-(3-Fluoro-4-Methoxyphenyl)acetic acid  pictures 2025-12-12 2-(3-Fluoro-4-Methoxyphenyl)acetic acid
452-14-2
US $1.00-1.60 / KG 1KG 99%+ 10000KG Shaanxi Dideu Medichem Co. Ltd
3-FLUORO-4-METHOXYPHENYLACETIC ACID pictures 2021-08-11 3-FLUORO-4-METHOXYPHENYLACETIC ACID
452-14-2
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
3-FLUORO-4-METHOXYPHENYLACETIC ACID 3-Fluoro-4-methyloxyphenylaceticacid 3-Fluoro-4-methoxyphenylacetic acid 98% 3-Fluoro-4-methoxyphenylaceticacid98% RARECHEM AL BO 1534 2-(3-fluoro-4-methoxyphenyl)acetic acid 4-(3-Fluoro-4-Methyloxyphenylacetic acid 4-(Carboxymethyl)-2-fluoroanisole 2-(3-fluoro-4-methoxy-phenyl)ethanoic acid 3F-4-METHOXYPHENYLESSIGSRE 5 G Benzeneacetic acid, 3-fluoro-4-methoxy- 452-14-2 Fluorine series Aromatic Phenylacetic Acids and Derivatives Phenylacetic acid