3-Fluoro-4-methoxyphenylacetic acid
- CAS No.
- 452-14-2
- Chemical Name:
- 3-Fluoro-4-methoxyphenylacetic acid
- Synonyms
- RARECHEM AL BO 1534;3F-4-METHOXYPHENYLESSIGSRE 5 G;4-(Carboxymethyl)-2-fluoroanisole;3-FLUORO-4-METHOXYPHENYLACETIC ACID;3-Fluoro-4-methyloxyphenylaceticacid;3-Fluoro-4-methoxyphenylaceticacid98%;Benzeneacetic acid, 3-fluoro-4-methoxy-;2-(3-fluoro-4-methoxyphenyl)acetic acid;3-Fluoro-4-methoxyphenylacetic acid 98%;4-(3-Fluoro-4-Methyloxyphenylacetic acid
- CBNumber:
- CB0104052
- Molecular Formula:
- C9H9FO3
- Molecular Weight:
- 184.16
- MDL Number:
- MFCD00060353
- MOL File:
- 452-14-2.mol
| Product description | Number | Pack Size | Price |
| 3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) | 8.43872 | 5G | $61 |
| 3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) | 8.43872 | 10g | $149 |
| 3-Fluoro-4-methoxyphenylacetic acid | F599325 | 250mg | $45 |
| 3-Fluoro-4-methoxyphenylacetic acid | J98090 | 5g | $11 |
| 3-Fluoro-4-methoxyphenylacetic acid 98% | PC3802 | 5g | $15 |
| More product size | |||
| Melting point | 111-113°C |
|---|---|
| Boiling point | 309.0±27.0 °C(Predicted) |
| Density | 1.269±0.06 g/cm3(Predicted) |
| storage temp. | Store below +30°C. |
| pka | 4.25±0.10(Predicted) |
| form | powder |
| color | White to off-white |
| InChI | 1S/C9H9FO3/c1-13-8-3-2-6(4-7(8)10)5-9(11)12/h2-4H,5H2,1H3,(H,11,12)/p-1 |
| InChIKey | VURNBRZIFABCRU-UHFFFAOYSA-M |
| SMILES | Fc1c(ccc(c1)CC(=O)[O-])OC |
| CAS DataBase Reference | 452-14-2(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | WGK 1 |
| HazardClass | IRRITANT |
| HS Code | 2918290090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1 |
3-Fluoro-4-methoxyphenylacetic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.43872 | 3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) | 452-14-2 | 5G | $61 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.43872 | 3-Fluoro-4-methoxyphenylacetic acid ≥99% (HPLC) | 452-14-2 | 10g | $149 | 2023-01-07 | Buy |
| TRC | F599325 | 3-Fluoro-4-methoxyphenylacetic acid | 452-14-2 | 250mg | $45 | 2021-12-16 | Buy |
| AK Scientific | J98090 | 3-Fluoro-4-methoxyphenylacetic acid | 452-14-2 | 5g | $11 | 2021-12-16 | Buy |
| Apolloscientific | PC3802 | 3-Fluoro-4-methoxyphenylacetic acid 98% | 452-14-2 | 5g | $15 | 2021-12-16 | Buy |
3-Fluoro-4-methoxyphenylacetic acid Chemical Properties,Uses,Production
Synthesis
3-fluoro-4-methoxyphenylacetonitrile (42 g, 0.25 mol) was heated for 5 h with 32 g of potassium hydroxide solution in 120 mL of ethanol and 30 mL of water. After the distillation of ethanol, the residue was diluted with water to a volume of 175 mL. The solution was filtered over the charcoal, and the filtrate was acidified by 50 percent H2SO4. The resulting solid was filtered and dried, yielding 3-Fluoro-4-methoxyphenylacetic acid.
References
[1] Collection of Czechoslovak Chemical Communications, 1990, vol. 55, # 1, p. 296 - 306
[2] European Journal of Medicinal Chemistry, 2014, vol. 87, p. 508 - 518
[3] Monatshefte fuer Chemie, 1955, vol. 86, p. 511,515
[4] DRP/DRBP Org.Chem.,
[5] Chemische Berichte, 1952, vol. 85, p. 577,580
3-Fluoro-4-methoxyphenylacetic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3591 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9999 | 58 |
View Lastest Price from 3-Fluoro-4-methoxyphenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-12 | 3-Fluoro-4-methoxyphenylacetic acid
452-14-2
|
US $55.00-15.00 / KG | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2025-12-12 | 2-(3-Fluoro-4-Methoxyphenyl)acetic acid
452-14-2
|
US $1.00-1.60 / KG | 1KG | 99%+ | 10000KG | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2021-08-11 | 3-FLUORO-4-METHOXYPHENYLACETIC ACID
452-14-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 3-Fluoro-4-methoxyphenylacetic acid
452-14-2
- US $55.00-15.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- 2-(3-Fluoro-4-Methoxyphenyl)acetic acid
452-14-2
- US $1.00-1.60 / KG
- 99%+
- Shaanxi Dideu Medichem Co. Ltd
-

- 3-FLUORO-4-METHOXYPHENYLACETIC ACID
452-14-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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