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ChemicalBook >> CAS DataBase List >>2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Structure
2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- structure
CAS No.
1110767-45-7
Chemical Name:
2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-
Synonyms
Butyzamide;CAS:1110767-45-7;(E)-3-(2,6-Dichloro-4-((4-(3-(2,2-dimethyl-1-pr opoxypropyl)-2-methoxyphenyl)thiazol-2-yl)car bamoyl)phenyl)-2-methylacrylic acid;(E)-3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]-oxomethyl]phenyl]-2-methyl-2-propenoic acid;2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-
CBNumber:
CB010407208
Molecular Formula:
C29H32Cl2N2O5S
Molecular Weight:
591.55
MDL Number:
MOL File:
1110767-45-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-30 11:39:11
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2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Properties

Density 1.299±0.06 g/cm3(Predicted)
pka 4.33±0.21(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0638558 Butyzamide 99.83% 1110767-45-7 1mg $211 2026-06-04 Buy
ChemScene CS-0638558 Butyzamide 99.83% 1110767-45-7 5mg $368 2026-06-04 Buy
ChemScene CS-0638558 Butyzamide 99.83% 1110767-45-7 10mg $542 2026-06-04 Buy
ChemScene CS-0638558 Butyzamide 99.83% 1110767-45-7 25mg $834 2026-06-04 Buy
ChemScene CS-0638558 Butyzamide 99.83% 1110767-45-7 50mg $1251 2026-06-04 Buy
Product number Packaging Price Buy
CS-0638558 1mg $211 Buy
CS-0638558 5mg $368 Buy
CS-0638558 10mg $542 Buy
CS-0638558 25mg $834 Buy
CS-0638558 50mg $1251 Buy

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Chemical Properties, Uses, Production

Uses

Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay[1].

in vivo

Butyzamide (10 mg/kg, 50 mg/kg; p.o.; once daily for 20 days) increases human platelets in NOG mice transplanted with human fetal liver-derived CD34+ cells[1].

IC 50

JAK2; STAT3; STAT5

References

[1] Nogami W, et al. The effect of a novel, small non-peptidyl molecule butyzamide on human thrombopoietin receptor and megakaryopoiesis. Haematologica. 2008 Oct;93(10):1495-504. DOI:10.3324/haematol.12752

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Suppliers

Global Suppliers ( 38)
Supplier Tel Email Country ProdList Advantage
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652 sales@meilune.com China 4765 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Anya Pharmaceutical Technology Co., LTD 19106202509 3626423147@qq.com China 1000 58
Zhengzhou Convergence Chemical Co. LTD 13393710386 3941078109@qq.com China 9860 58
Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. 15720605021 zhang_lei@jsnchem.com China 1881 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7998 58
Supplier Advantage
Dalian Meilun Biotech Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Rechem science Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
TargetMol Chemicals Inc. 58
Shanghai Anya Pharmaceutical Technology Co., LTD 58
Zhengzhou Convergence Chemical Co. LTD 58
Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. 58
Hubei Kele Fine Chemical Co., Ltd 58

View Latest Price from 2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Butyzamide pictures 2026-08-30 Butyzamide
1110767-45-7
 $160.00-413.00 99.51% 10g TargetMol Chemicals Inc.
  • Butyzamide pictures
  • Butyzamide
    1110767-45-7
  • $160.00-413.00
  • 99.51%
  • TargetMol Chemicals Inc.

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Spectrum

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-(1110767-45-7)1HNMR

1110767-45-7 (2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)-) Related Search:

2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Lusutrombopag Lusutrombopag Ruxolitinib NA
GYY 4137 Morpholine salt

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2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- Butyzamide (E)-3-(2,6-Dichloro-4-((4-(3-(2,2-dimethyl-1-pr opoxypropyl)-2-methoxyphenyl)thiazol-2-yl)car bamoyl)phenyl)-2-methylacrylic acid (E)-3-[2,6-dichloro-4-[[[4-[3-(2,2-dimethyl-1-propoxypropyl)-2-methoxyphenyl]-2-thiazolyl]amino]-oxomethyl]phenyl]-2-methyl-2-propenoic acid CAS:1110767-45-7 1110767-45-7