3-Bromo-2-fluorobenzonitrile
- CAS No.
- 840481-82-5
- Chemical Name:
- 3-Bromo-2-fluorobenzonitrile
- Synonyms
- 3-Bromo-2-fluorobenzonitrile;Benzonitrile, 3-broMo-2-fluoro-;1-Bromo-3-cyano-2-fluorobenzene;3-BROMO-2-FLUOROBENZONITRILE 96%;Benzonitrile, 3-bromo-2-fluoro- (9CI);KaiXinTianRui Technology Development Co., Ltd
- CBNumber:
- CB01047006
- Molecular Formula:
- C7H3BrFN
- Molecular Weight:
- 200.01
- MDL Number:
- MFCD06657980
- MOL File:
- 840481-82-5.mol
- MSDS File:
- SDS
| Melting point | 37-40°C |
|---|---|
| Boiling point | 221.9±20.0 °C(Predicted) |
| Density | 1.69±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | crystalline powder |
| color | Very faint orange |
| InChI | InChI=1S/C7H3BrFN/c8-6-3-1-2-5(4-10)7(6)9/h1-3H |
| InChIKey | AMKVZJOQZLIOSL-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC=CC(Br)=C1F |
| CAS DataBase Reference | 840481-82-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xi |
| RIDADR | 3439 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2926907090 |
| Limited Quantities | 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
3-Bromo-2-fluorobenzonitrile price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 261921 | 3-Bromo-2-fluorobenzonitrile Asreported | 840481-82-5 | 2g | $322 | 2026-06-03 | Buy |
| Usbiological | 261921 | 3-Bromo-2-fluorobenzonitrile Asreported | 840481-82-5 | 5g | $440 | 2026-06-03 | Buy |
| Usbiological | 261921 | 3-Bromo-2-fluorobenzonitrile Asreported | 840481-82-5 | 10g | $588 | 2026-06-03 | Buy |
| Usbiological | 261921 | 3-Bromo-2-fluorobenzonitrile Asreported | 840481-82-5 | 25g | $779 | 2026-06-03 | Buy |
| Usbiological | 261921 | 3-Bromo-2-fluorobenzonitrile Asreported | 840481-82-5 | 50g | $1097 | 2026-06-03 | Buy |
3-Bromo-2-fluorobenzonitrile Chemical Properties,Uses,Production
Uses
3-Bromo-2-fluorobenzonitrile is an organic intermediate that can be prepared from 3-bromo-2-fluorobenzoic acid in two steps. 3-Bromo-2-fluorobenzonitrile can be used as a pharmaceutical intermediate in the preparation of STK4 inhibitors.
Synthesis
To a N, N-dimethylformamide solution (10 mL) of 3-bromo-2- fluorobenzamide (867 mg) was added to cyanuric chloride (806 mg) under ice-cooling, and the mixture was stirred overnight at room temperature. The mixture was diluted with ethyl acetate, and the organic layer was washed with water and saturated brine, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. Purification by silica gel column chromatography (hexane: ethyl acetate = 1:0 - 1:1) gave 3-Bromo-2-fluorobenzonitrile (760 mg, yield 96%) as colorless crystals.
References
[1] Patent: WO2008/156757, 2008, A1. Location in patent: Page/Page column 139
[2] Patent: WO2016/161145, 2016, A1. Location in patent: Paragraph 00753
3-Bromo-2-fluorobenzonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| WUXI SHUANGQI TECHNOLOGY CO LTD. | 0510-86529556 18114865355 | 1702606491@qq.com | China | 1103 | 58 |
| Jalor-Chem co.,LTD | 0510-0510-86396359 13382276200 | sales@jalor-chem.com | China | 1000 | 56 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Changzhou Huanling Chemical Co., Ltd. | 89803005 18206112582 | info@huanlingchem.com | China | 983 | 68 |
View Lastest Price from 3-Bromo-2-fluorobenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | Benzonitrile, 3-bromo-2-fluoro- (9CI)
840481-82-5
|
$10.00 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-05-26 | Benzonitrile, 3-bromo-2-fluoro- (9CI)
840481-82-5
|
$5.00 | 1kg | 0.99 | 10000 | Hebei Fengjia New Material Co., Ltd | |
 |
2019-07-10 | Benzonitrile, 3-bromo-2-fluoro- (9CI)
840481-82-5
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- Benzonitrile, 3-bromo-2-fluoro- (9CI)
840481-82-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Benzonitrile, 3-bromo-2-fluoro- (9CI)
840481-82-5
- $5.00
- 0.99
- Hebei Fengjia New Material Co., Ltd
-
- Benzonitrile, 3-bromo-2-fluoro- (9CI)
840481-82-5
- $1.00
- 98%
- Career Henan Chemical Co
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