4,6-Dichloropyridine-3-acetonitrile
- CAS No.
- 199283-52-8
- Chemical Name:
- 4,6-Dichloropyridine-3-acetonitrile
- Synonyms
- 3-Pyridineacetonitrile, 4,6-dichloro-;2-(4,6-Dichloro-3-pyridyl)acetonitrile;(4,6-Dichloro-3-Pyridinyl)Acetonitrile;2-(4,6-DICHLOROPYRIDIN-3-YL)ACETONITRILE
- CBNumber:
- CB01074150
- Molecular Formula:
- C7H4Cl2N2
- Molecular Weight:
- 187.03
- MDL Number:
- MOL File:
- 199283-52-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
4,6-Dichloropyridine-3-acetonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | D44323 | 2-(4,6-Dichloropyridin-3-yl)acetonitrile 95+% | 199283-52-8 | 100mg | $80 | 2026-05-06 | Buy |
| Synthonix | D44323 | 2-(4,6-Dichloropyridin-3-yl)acetonitrile 95+% | 199283-52-8 | 250mg | $160 | 2026-05-06 | Buy |
| Synthonix | D44323 | 2-(4,6-Dichloropyridin-3-yl)acetonitrile 95+% | 199283-52-8 | 1g | $440 | 2026-05-06 | Buy |
| aablocks | AA002BY6 | 2-(4,6-Dichloropyridin-3-Yl)Acetonitrile 98% | 199283-52-8 | 100mg | $53 | 2026-05-28 | Buy |
| aablocks | AA002BY6 | 2-(4,6-Dichloropyridin-3-Yl)Acetonitrile 98% | 199283-52-8 | 250mg | $108 | 2026-05-28 | Buy |
4,6-Dichloropyridine-3-acetonitrile Chemical Properties,Uses,Production
Synthesis
7677-24-9
1227606-01-0
199283-52-8
Step 2: 5-(bromomethyl)-2,4-dichloropyridine (0.500 g, 1.87 mmol) was dissolved in acetonitrile (5.0 mL). To this solution was added sodium hydroxide monohydrate (UOH-H2O, 0.0960 g, 2.24 mmol) followed by slow dropwise addition of trimethylcyanosilane (0.280 mL, 2.24 mmol). The reaction mixture was stirred continuously at room temperature for 2 hours. After completion of the reaction, the reaction solution was diluted with ethyl acetate. The diluted solution was washed twice with water. The organic phase was dried over anhydrous sodium sulfate, then the filtrate was filtered and concentrated to give a yellow oily crude product (394 mg). The crude product was purified by fast column chromatography (eluent: cyclohexane/ethyl acetate, 4:1) to afford the target product 2-(4,6-dichloropyridin-3-yl)acetonitrile (329 mg) in white solid form. The product was characterized by 1H-NMR (CDCl3): δ 8.5 (s, 1H), 7.47 (s, 1H), 3.82 (s, 2H).
References
[1] Patent: WO2013/64521, 2013, A1. Location in patent: Page/Page column 110
4,6-Dichloropyridine-3-acetonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
4,6-Dichloropyridine-3-acetonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189;18621755571 | mychess007@163.com | China | 1994 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 6736 | 58 |
| Shanghai Kaiwei Chemical Technology Co., Ltd. | 021-58461859 15821823057 | service@aiviche.com | China | 49299 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Xi'an Zhenghao Biotechnology Co., Ltd | 19829389091 | 399787610@qq.com | China | 2506 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39796 | 58 |
| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39645 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 17801761073 | Gsiyu@solarbio.com | China | 50460 | 58 |
