5-Bromo-3-Methoxy-Pyridine2-Carbonitrile
- CAS No.
- 36057-46-2
- Chemical Name:
- 5-Bromo-3-Methoxy-Pyridine2-Carbonitrile
- Synonyms
- 5-Bromo-3-methoxypicolinonitrile;5-Bromo-3-Methoxy-Pyridine2-Carbonitrile;5-Bromo-3-methoxy-2-pyridinecarbonitrile;2-Pyridinecarbonitrile, 5-bromo-3-methoxy-
- CBNumber:
- CB01074680
- Molecular Formula:
- C7H5BrN2O
- Molecular Weight:
- 213.03
- MDL Number:
- MFCD11857636
- MOL File:
- 36057-46-2.mol
- MSDS File:
- SDS
| Boiling point | 310.9±37.0 °C(Predicted) |
|---|---|
| Density | 1.65±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | -7.15±0.10(Predicted) |
| Appearance | White to yellow Solid |
| InChI | InChI=1S/C7H5BrN2O/c1-11-7-2-5(8)4-10-6(7)3-9/h2,4H,1H3 |
| InChIKey | WIRVBLLSXJUOHZ-UHFFFAOYSA-N |
| SMILES | C1(C#N)=NC=C(Br)C=C1OC |
| UNSPSC Code | 12352200 |
5-Bromo-3-Methoxy-Pyridine2-Carbonitrile price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | ADE000496 | 5-Bromo-3-methoxypicolinonitrile Aldrich | 36057-46-2 | 1g | $870 | 2026-04-30 | Buy |
| Biosynth | LBA05746 | 5-Bromo-3-methoxy-pyridine 2-carbonitrile | 36057-46-2 | 2.5g | $413 | 2026-06-04 | Buy |
| Matrix Scientific | 314008 | 5-Bromo-3-methoxypyridine 2-carbonitrile | 36057-46-2 | 250.00mg | $54 | 2026-05-19 | Buy |
| Matrix Scientific | 314008 | 5-Bromo-3-methoxypyridine 2-carbonitrile | 36057-46-2 | 1.00g | $93 | 2026-05-19 | Buy |
| Matrix Scientific | 314008 | 5-Bromo-3-methoxypyridine 2-carbonitrile | 36057-46-2 | 5.00g | $313 | 2026-05-19 | Buy |
5-Bromo-3-Methoxy-Pyridine2-Carbonitrile Chemical Properties, Uses, Production
Synthesis
886373-28-0
124-41-4
36057-46-2
Sodium methanolate (2.68 g, 49.59 mmol) was added to a solution of 5-bromo-3-fluoropyridine-2-carbonitrile (2.00 g, 9.93 mmol) in tetrahydrofuran (THF, 80 mL) at room temperature. The reaction mixture was stirred at 70 °C for 3 hours. Upon completion of the reaction, the pH of the reaction mixture was adjusted to 7 with a 3 M solution of HCl. The reaction mixture was extracted with ethyl acetate (100 mL x 3). The organic phases were combined, washed with brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give 5-bromo-3-methoxypyridine-2-carbonitrile as a brown solid (2.00 g, 95% yield). Mass spectrum (MS): m/z = 213.0 [M + H]+.
References
[1] Patent: US2016/376283, 2016, A1. Location in patent: Paragraph 1219; 1220
[2] Patent: EP3275864, 2018, A1. Location in patent: Paragraph 0032; 0038; 0044; 0050; 0056; 0062
[3] Patent: WO2007/87488, 2007, A2. Location in patent: Page/Page column 24
5-Bromo-3-Methoxy-Pyridine2-Carbonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hansi Chemical Industry Co., Ltd. | 17717618050 | zllg@gh-reagent.com | China | 10418 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Changzhou Wanyao Biotechnology Co., Ltd. | 0519-89185693 15312551983 | 2410037592@qq.com | China | 278 | 55 |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 997 | 59 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189;18621755571 | mychess007@163.com | China | 1994 | 55 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Tcichem, Inc. | 13918644899 | 81587635@qq.com | China | 1994 | 55 |
