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5-Bromo-3-nitropyridine-2-carbonitrile

5-Bromo-3-nitropyridine-2-carbonitrile Structure
5-Bromo-3-nitropyridine-2-carbonitrile structure
CAS No.
573675-25-9
Chemical Name:
5-Bromo-3-nitropyridine-2-carbonitrile
Synonyms
6500/20KG DZ;5-Bromo-2-cyano-3-nitropy...;5-Bromo-3-nitro-2-cynopyridine;5-Bromo-2-Cyano-3-Nitropyridne;5-BROMO-3-NITRO-2-CYANOPYRIDINE;5-BROMO-2-CYANO-3-NITROPYRIDINE;2-Cyano-5-bromo-3-nitropyridine;5-Bromo-3-nitropyridin-2-carbonitrile;5-BROMO-3-NITROPYRIDINE-2-CARBONITRILE;5-Bromo-3-nitro-2-pyridinecarbonitrile
CBNumber:
CB0260657
Molecular Formula:
C6H2BrN3O2
Molecular Weight:
228
MDL Number:
MFCD06657551
MOL File:
573675-25-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-04 16:00:12
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5-Bromo-3-nitropyridine-2-carbonitrile Properties

Melting point 101-106 °C
Boiling point 348.9±42.0 °C(Predicted)
Density 1.92±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka -6.71±0.20(Predicted)
form powder to crystal
color Light orange to Yellow to Green
InChI InChI=1S/C6H2BrN3O2/c7-4-1-6(10(11)12)5(2-8)9-3-4/h1,3H
InChIKey OBVYONPVHIOJJZ-UHFFFAOYSA-N
SMILES C1(C#N)=NC=C(Br)C=C1[N+]([O-])=O
CAS DataBase Reference 573675-25-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H312+H332-H315-H318-H335
Precautionary statements  P261-P280-P301+P310-P302+P352+P312-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes  T,Xi
Risk Statements  20/21-25-37/38-41
Safety Statements  26-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
Hazard Note  Toxic
HazardClass  IRRITANT
PackingGroup  Ⅲ
HS Code  29333990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
0
2 0

5-Bromo-3-nitropyridine-2-carbonitrile price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 662968 5-Bromo-3-nitropyridine-2-carbonitrile 95% 573675-25-9 5g $33.8 2026-04-30 Buy
Sigma-Aldrich 662968 5-Bromo-3-nitropyridine-2-carbonitrile 95% 573675-25-9 25g $127 2026-04-30 Buy
TCI Chemical B5584 5-Bromo-2-cyano-3-nitropyridine >98.0%(GC) 573675-25-9 5g $63 2026-04-30 Buy
TCI Chemical B5584 5-Bromo-2-cyano-3-nitropyridine >98.0%(GC) 573675-25-9 25g $248 2026-04-30 Buy
Biosynth NB67409 5-Bromo-2-cyano-3-nitropyridine 573675-25-9 0.025kg $150 2026-06-04 Buy
Product number Packaging Price Buy
662968 5g $33.8 Buy
662968 25g $127 Buy
B5584 5g $63 Buy
B5584 25g $248 Buy
NB67409 0.025kg $150 Buy

5-Bromo-3-nitropyridine-2-carbonitrile Chemical Properties, Uses, Production

Chemical Properties

Yellow to light yellow crystals

Uses

Used as an intermediate in organic synthesis.

Synthesis

To a stirred solution of 2,5-dibromo-3-nitro-pyridine (25 g, 88.68 mmol) in propionitrile (100 ml) was added CuCN (8.7 g, 97.55 mmol) and the mixture was heated to 90°C. for 17 h. Then it was allowed to cool to room temperature, diluted with EtOAc, washed twice with brine, dried with Na2SO4 and concentrated. The remaining residue was purified by chromatography (silica gel; DCM/MeOH 95:5- 85:15) to obtain 5-Bromo-3-nitropyridine-2-carbonitrile. Yellow solid, yield 17.5 g, 68%.
synthesis of 5-Bromo-3-nitropyridine-2-carbonitrile

References

[1] Patent: EP1757594, 2007, A1. Location in patent: Page/Page column 76
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 13, p. 3608 - 3612
[3] Patent: WO2005/42498, 2005, A2. Location in patent: Page/Page column 43; 44
[4] Patent: WO2006/52514, 2006, A1. Location in patent: Page/Page column 7-8
[5] Patent: WO2006/132837, 2006, A1. Location in patent: Page/Page column 19

5-Bromo-3-nitropyridine-2-carbonitrile synthesis

15862-37-0
544-92-3
573675-25-9
Synthesis of 5-Bromo-3-nitropyridine-2-carbonitrile from 2,5-Dibromo-3-nitropyridine and Copper(I) Cyanide

5-Bromo-3-nitropyridine-2-carbonitrile Preparation Products And Raw materials

Raw materials

2,5-Dibromo-3-nitropyridine copper(II) cyanide 2-Amino-5-bromo-3-nitropyridine 5-Bromo-3-nitro-2-pyridinol Copper(I) Cyanide

Preparation Products

7-Bromo-2,4-dichloropyrido[3,2-d]pyrimidine 5-Bromo-3-Methoxy-Pyridine2-Carbonitrile 7-bromo-4-chloropyrido[3,2-d]pyrimidine 1-(5-Bromo-3-fluoropyridin-2-yl)ethanone 5-Bromo-3-fluoro-pyridine-2-carbonitrile
3-(Benzyloxy)-5-bromopicolinonitrile 5-BroMo-3-nitropyridine-2-carboxaMide

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5-Bromo-3-nitropyridine-2-carbonitrile Suppliers

Global Suppliers ( 330)
Supplier Tel Email Country ProdList Advantage
Shanghai EachChem Co., Ltd. 021-64196659 13564486206 info@eachchem.com China 50 55
FUXIN QINGJISHENG SCIENCE AND TECHNOLOGY CO.,LID 15940530539 15396717197 361811402@qq.com China 650 58
Fuxin Fengcheng Chemical Technology Development Co., Ltd. 0418-2868000 13464847801 jingxuan.lu@fcmeditech.com China 343 55
Shandong Zhishang Chemical Co. LTD 15689709505 15508639737 2138533552@qq.com China 102 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Supplier Advantage
Shanghai EachChem Co., Ltd. 55
FUXIN QINGJISHENG SCIENCE AND TECHNOLOGY CO.,LID 58
Fuxin Fengcheng Chemical Technology Development Co., Ltd. 55
Shandong Zhishang Chemical Co. LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65
Wuhan Chemwish Technology Co., Ltd 56

View Latest Price from 5-Bromo-3-nitropyridine-2-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Bromo-3-nitropyridine-2-carbonitrile pictures 2026-09-02 5-Bromo-3-nitropyridine-2-carbonitrile
573675-25-9
 $6.00 1KG 98% Henan Fengda Chemical Co., Ltd
5-Bromo-3-nitropyridine-2-carbonitrile pictures 2026-08-07 5-Bromo-3-nitropyridine-2-carbonitrile
573675-25-9
 1KG 98% 1MT Shaanxi Dideu Medichem Co. Ltd
5-Bromo-3-nitropyridine-2-carbonitrile pictures 2026-06-30 5-Bromo-3-nitropyridine-2-carbonitrile
573675-25-9
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

5-Bromo-3-nitropyridine-2-carbonitrile Spectrum

5-Bromo-3-nitropyridine-2-carbonitrile(573675-25-9)1HNMR

573675-25-9 (5-Bromo-3-nitropyridine-2-carbonitrile) Related Search:

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5-Bromo-3-nitro-2-cynopyridine 5-Bromo-2-cyano-3-nitropy... 2-Cyano-5-bromo-3-nitropyridine 5-BROMO-2-CYANO-3-NITROPYRIDINE 5-BROMO-3-NITRO-2-CYANOPYRIDINE 5-BROMO-3-NITROPYRIDINE-2-CARBONITRILE 573675-25-92-PYRIDINECARBONITRILE, 5-BROMO-3-NITRO- 5-Bromo-3-nitropicolinonitrile, 5-Bromo-2-cyano-3-nitropyridine 2-Pyridinecarbonitrile, 5-bromo-3-nitro- 6500/20KG DZ 5-Bromo-3-nitropyridine-2-carbonitrile ISO 9001：2015 REACH 5-Bromo-2-Cyano-3-Nitropyridne 5-Bromo-3-nitro-2-pyridinecarbonitrile 5-Bromo-3-nitropyridin-2-carbonitrile 5-Bromo-3-nitropyridine-2-carbonitrile, 98% 573675-25-9 573675-25-0 C6H2BrN3O2 Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Pyridines, Pyrimidines, Purines and Pteredines Pyridine series Pyridine Pyridines