ChemicalBook >> CAS DataBase List >>2-BROMO-6-NITROANILINE

2-BROMO-6-NITROANILINE

2-BROMO-6-NITROANILINE structure

CAS No.: 59255-95-7

Chemical Name:: 2-BROMO-6-NITROANILINE

Synonyms: Bromo-6-nitroaniline;2-Nitro-6-Bromoaniline;2-BROMO-6-NITROANILINE;6-bromo-2-nitro-aniline;2-broMo-6-nitrobenzenaMine;2-Bromo-6-nitroaniline 99%;2-Amino-3-bromonitrobenzene;Benzenamine, 2-bromo-6-nitro-

CBNumber:: CB01092086

Molecular Formula:: C6H5BrN2O2

Molecular Weight:: 217.02

MDL Number:: MFCD09263476

MOL File:: 59255-95-7.mol

Last updated:2025-08-08 17:45:00

Product description	Number	Pack Size	Price
2-Bromo-6-nitroaniline 97.0%	CS-W006849	1g	$28
2-Bromo-6-nitroaniline 99%	OR11720	1g	$54
2-Bromo-6-nitroaniline 99.0%	4655-9-Y6	1g	$60
2-Bromo-6-nitroaniline	W7219	1g	$92
2-Bromo-6-nitroaniline 95+%	076490	1g	$124

Request For Quotation

2-BROMO-6-NITROANILINE Properties

Melting point	74.5°C
Boiling point	309.8±22.0 °C(Predicted)
Density	1.7917 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	-2.46±0.25(Predicted)
form	solid
color	Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2921420090

2-BROMO-6-NITROANILINE price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-W006849	2-Bromo-6-nitroaniline 97.0%	59255-95-7	1g	$28	2021-12-16	Buy
Apolloscientific	OR11720	2-Bromo-6-nitroaniline 99%	59255-95-7	1g	$54	2021-12-16	Buy
SynQuest Laboratories	4655-9-Y6	2-Bromo-6-nitroaniline 99.0%	59255-95-7	1g	$60	2021-12-16	Buy
AK Scientific	W7219	2-Bromo-6-nitroaniline	59255-95-7	1g	$92	2021-12-16	Buy
Matrix Scientific	076490	2-Bromo-6-nitroaniline 95+%	59255-95-7	1g	$124	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-W006849	1g	$28	Buy
OR11720	1g	$54	Buy
4655-9-Y6	1g	$60	Buy
W7219	1g	$92	Buy
076490	1g	$124	Buy

2-BROMO-6-NITROANILINE Chemical Properties,Uses,Production

Chemical Properties

Pale yellow powder

Uses

2-Bromo-6-nitroaniline, is an intermediate used for the synthesis of metabolite of Brimonidine (B677520), which is an α2 receptor agonist. It is a drug used to treat glaucoma.

Synthesis

88-74-4

59255-95-7

875-51-4

N-bromosuccinimide (44.5 g, 0.25 mol) was added to a solution of 2-nitroaniline (34.5 g, 0.25 mol) in acetic acid (400 mL) in batches over a period of 30 minutes over a temperature range of 308-318 K. The reaction mixture was stirred continuously for 3 hours. The reaction mixture was stirred continuously at 318 K for 3 hours, followed by warming to 363 K and continued stirring for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and poured into vigorously stirred cold water (4 L). After standing for 10 min, the orange precipitate was collected by filtration and washed with cold water (2 x 200 mL). The crude product was recrystallized by 80% ethanol and dried under vacuum to give pure 4-bromo-2-nitroaniline (39.9 g, 74% yield) as an orange crystalline solid. A second crystalline product (6.81 g) was isolated from the mother liquor and analyzed as a mixture of 4-bromo-2-nitroaniline and 2-bromo-6-nitroaniline (ratio 1:0.3). The nuclear magnetic resonance hydrogen spectroscopy (1H NMR) data were in agreement with those reported in the literature (Manley et al., 2003; Lemaire et al., 1989).The 1H NMR (300 MHz, CDCl3) data for 4-bromo-2-nitroaniline: δ 8.26 (dd, J = 2.3, 0.4 Hz, 1H), 7.42 (dd, J = 8.9 , 2.3 Hz, 1H), 6.73 (dd, J = 8.9, 0.4 Hz, 1H), 6.10 (s, 2H).1H NMR (400 MHz, CDCl3) data for 2-bromo-6-nitroaniline: δ 8.14 (dd, J = 8.7, 1.5 Hz, 1H), 7.70 (dd, J = 7.7, 1.5 Hz, 1H), 6.63 (s, 2H). 6.63 (s, 2H), 6.62 (dd, J = 8.7, 7.7 Hz, 1H). Single crystals of 4-bromo-2-nitroaniline and 2-bromo-6-nitroaniline were obtained by sublimation of the second crystallization product (from chloroform) and slow evaporation under reduced pressure conditions (323 K, 10 mbar; 1 bar = 105 Pa), respectively.

References

[1] Polyhedron, 2013, vol. 52, p. 246 - 254
[2] Synthetic Communications, 2000, vol. 30, # 20, p. 3669 - 3675
[3] Acta Crystallographica Section C: Structural Chemistry, 2018,
[4] Synthetic Communications, 2004, vol. 34, # 12, p. 2143 - 2152
[5] Tetrahedron Letters, 2012, vol. 53, # 2, p. 127 - 131

2-BROMO-6-NITROANILINE synthesis

Synthesis of 2-BROMO-6-NITROANILINE from 3-BROMO-2-FLUORONITROBENZENE

2-BROMO-6-NITROANILINE Preparation Products And Raw materials

Raw materials

4-Bromo-2-nitroaniline AcetaMide, N-(2-broMo-6-nitrophenyl)- 2,4-Dibromo-6-nitroaniline 2'-BROMOACETANILIDE 1,2-DibroMo-3-nitrobenzene

1-Bromo-2-methoxy-3-nitro-benzene 2-BROMO-4-NITROANILINE 3-BROMO-2-FLUORONITROBENZENE 2-Nitroaniline

1of2

Preparation Products

3-bromo-2-chloroaniline 2-Amino-7-bromobenzothiazole 2-broMo-4-iodo-6-nitro-aniline

2-BROMO-6-NITROANILINE Suppliers

Global( 133)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 +86-17392581500	1015@dideu.com	China	3986	58
Shanghai Safer Pharmaceutical Technology Co., Ltd.	021-31761238	sales@saferph.com	CHINA	897	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Changzhou Ansciep Chemical Co., Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanghai Safer Pharmaceutical Technology Co., Ltd.	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58

View Lastest Price from 2-BROMO-6-NITROANILINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-01-04	2-BROMO-6-NITROANILINE 59255-95-7	US $0.00 / kg	1kg	98%	2000kg	Hangzhou ICH Biofarm Co., Ltd
	2019-12-24	2-BROMO-6-NITROANILINE 59255-95-7	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

2-BROMO-6-NITROANILINE
59255-95-7
US $0.00 / kg
98%
Hangzhou ICH Biofarm Co., Ltd

2-BROMO-6-NITROANILINE
59255-95-7
US $1.00 / KG
99%
Career Henan Chemical Co

2-BROMO-6-NITROANILINE Spectrum

2-BROMO-6-NITROANILINE(59255-95-7)¹HNMR

59255-95-7(2-BROMO-6-NITROANILINE)Related Search:

Disperse Blue 79 2-BROMO-4-CHLORO-6-NITROPHENYLAMINE 2-Bromo-4,6-dinitroaniline 2,4-Dibromo-6-nitroaniline 2-BROMO-4-METHYL-6-NITROANILINE

4-AMINO-3-BROMO-5-NITROBENZOTRIFLUORIDE 3-Bromonitrobenzene Disperse Blue 291 2-BROMO-4-FLUORO-6-NITROANILINE 2-BROMO-6-NITROANILINE

Disperse Blue 94 2-Bromo-6-nitro-4-trifluoromethoxyaniline 2-BROMO-4-TRIFLUOROMETHYL-6-NITROPHENYLISOTHIO-CYANATE DISPERSE BLUE 79:1 BUTTPARK 62\11-04

METHYL 4-AMINO-3-BROMO-5-NITROBENZENECARBOXYLATE N-(6-BROMO-2,3-DIHYDRO-4-NITRO-1-OXO-1H-INDEN-5-YL)ACETAMIDE N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-[(2-hydroxy-3-methoxypropyl)amino]-4-methoxyphenyl]acetamide

1of4

2-BROMO-6-NITROANILINE 2-Amino-3-bromonitrobenzene 2-Bromo-6-nitroaniline 99% 2-broMo-6-nitrobenzenaMine Bromo-6-nitroaniline 6-bromo-2-nitro-aniline Benzenamine, 2-bromo-6-nitro- 2-Nitro-6-Bromoaniline 59255-95-7