2-Bromo-4-nitroaniline
- CAS No.
- 13296-94-1
- Chemical Name:
- 2-Bromo-4-nitroaniline
- Synonyms
- 2-bromo-4-nitro-anilin;AKOS BBB/074;BUTTPARK 147\16-92;TIMTEC-BB SBB007590;2-Brom-4-nitroanilin;6-Bromo-p-nitroaniline;2-Bromo-4-nitroaniline;Aniline, 2-bromo-4-nitro-;2-Bromo-4-nitrobenzenamine;2-BROMO-4-NITRO-PHENYLAMINE
- CBNumber:
- CB9422322
- Molecular Formula:
- C6H5BrN2O2
- Molecular Weight:
- 217.02
- MDL Number:
- MFCD00025152
- MOL File:
- 13296-94-1.mol
- MSDS File:
- SDS
| Melting point | 104°C |
|---|---|
| Boiling point | 351.8±22.0 °C(Predicted) |
| Density | 1.7917 (rough estimate) |
| refractive index | 1.5150 (estimate) |
| Flash point | 166℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -1.18±0.10(Predicted) |
| color | Dark Yellow |
| Stability | Hygroscopic |
| CAS DataBase Reference | 13296-94-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | Benzenamine, 2-bromo-4-nitro-(13296-94-1) |
| EPA Substance Registry System | 2-Bromo-4-nitroaniline (13296-94-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 23/24/25-33 | |||||||||
| Safety Statements | 28-37-45 | |||||||||
| RTECS | BW9350000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29214200 | |||||||||
| NFPA 704 |
|
2-Bromo-4-nitroaniline price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B4873 | 2-Bromo-4-nitroaniline >98.0%(GC) | 13296-94-1 | 1g | $36 | 2026-04-30 | Buy |
| TCI Chemical | B4873 | 2-Bromo-4-nitroaniline >98.0%(GC) | 13296-94-1 | 5g | $111 | 2026-04-30 | Buy |
| TRC | TRC-B687655-50G | 2-Bromo-4-nitroaniline | 13296-94-1 | 50g | $264 | 2026-06-03 | Buy |
| TRC | TRC-B687655-1G | 2-Bromo-4-nitroaniline | 13296-94-1 | 1g | $109 | 2026-06-03 | Buy |
| TRC | TRC-B687655-10G | 2-Bromo-4-nitroaniline | 13296-94-1 | 10g | $167 | 2026-06-03 | Buy |
2-Bromo-4-nitroaniline Chemical Properties, Uses, Production
Chemical Properties
Yellow solid
Uses
2-Bromo-4-nitroaniline is used as a reagent in the synthesis of novel tetrahydrothienopyridopyrimidine derivatives which exhibit antibacterial and antifungal activity against a variety of microorganisms in vitro. Also used as a reagent in synthesis of dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents.
Synthesis
100-01-6
13296-94-1
Bromine (2.05 mL, 40 mmol) was slowly added dropwise to a solution of 4-nitroaniline (5.0 g, 36 mmol) in acetic acid (150 mL) at room temperature and under argon protection. The reaction mixture was stirred continuously for 2 hours at room temperature. Upon completion of the reaction, the reaction was quenched with dilute aqueous sodium thiosulfate (150 mL) followed by extraction with ethyl acetate (2 x 500 mL). The organic layers were combined and carefully poured into saturated aqueous sodium bicarbonate solution (1 L) and stirred at room temperature for 30 min until the gas release stopped completely. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (petroleum ether/dichloromethane, 3:1) to afford 2-bromo-4-nitroaniline as a yellow solid (6.3 g, 80% yield).1H NMR (400 MHz, CDCl3) δ: 8.39 (1H, d, J = 2.4 Hz), 8.06 (1H, d, J = 2.4 Hz), 6.77 (1H, d, J = 9.2 Hz).
References
[1] Synthesis, 2004, # 17, p. 2809 - 2812
[2] Tetrahedron Letters, 2017, vol. 58, # 48, p. 4559 - 4562
[3] Tetrahedron Letters, 2005, vol. 46, # 51, p. 8959 - 8963
[4] Synthetic Communications, 2010, vol. 40, # 21, p. 3226 - 3232
[5] Journal of the American Chemical Society, 1994, vol. 116, # 26, p. 11797 - 11810
2-Bromo-4-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from 2-Bromo-4-nitroaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-02 | 2-BROMO-4-NITROANILINE
13296-94-1
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2022-01-15 | 2-Bromo-4-nitroaniline
13296-94-1
|
1KG | 97.9% | 100 tons | Honest Joy Holdings Limited | ||
![]() |
2020-02-26 | 2-Bromo-4-nitroaniline
13296-94-1
|
1KG | 99.0% | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-

- 2-BROMO-4-NITROANILINE
13296-94-1
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 2-Bromo-4-nitroaniline
13296-94-1
- $0.00
- 97.9%
- Honest Joy Holdings Limited
-

- 2-Bromo-4-nitroaniline
13296-94-1
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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