Crisnatol
- CAS No.
- 96389-68-3
- Chemical Name:
- Crisnatol
- Synonyms
- 770U-82;BW-A-770U;Crisnatol;Crisnatolum;Crisnatol [inn];Unii-2J71ur51ue;Crisnatolum [latin];2-((6-chrysenylmethyl)amino)-2-methyl-1,3-propanediol;2-(Chrysene-6-ylmethylamino)-2-methyl-1,3-propanediol;2-[(Chrysen-6-ylmethyl)amino]-2-methyl-1,3-propanediol
- CBNumber:
- CB01178384
- Molecular Formula:
- C23H23NO2
- Molecular Weight:
- 345.43
- MDL Number:
- MOL File:
- 96389-68-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Solid |
|---|---|
| color | White to off-white |
| FDA UNII | 2J71UR51UE |
Crisnatol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0619908 | Crisnatol 99.51% | 96389-68-3 | 5mg | $162 | 2026-06-04 | Buy |
| ChemScene | CS-0619908 | Crisnatol 99.51% | 96389-68-3 | 10mg | $260 | 2026-06-04 | Buy |
| ChemScene | CS-0619908 | Crisnatol 99.51% | 96389-68-3 | 25mg | $509 | 2026-06-04 | Buy |
| ChemScene | CS-0619908 | Crisnatol 99.51% | 96389-68-3 | 50mg | $812 | 2026-06-04 | Buy |
| ChemScene | CS-0619908 | Crisnatol 99.51% | 96389-68-3 | 100mg | $1300 | 2026-06-04 | Buy |
Crisnatol Chemical Properties, Uses, Production
Uses
Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3].
in vivo
Crisnatol (25 mg/kg; p.o.; single dose) shows oral activity and shows stable metabolite profile extract of rat feces by autoradiography[2].
References
[1] Adams DJ. In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator. Cancer Res. 1989 Dec 1;49(23):6615-20. PMID:1676660
[2] Patel DK, et al. Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. Biochem Pharmacol. 1991 Jul 5;42(2):337-46. DOI:10.1016/0006-2952(91)90721-g
[3] Patel DK, et al. Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat. Drug Metab Dispos. 1991 Mar-Apr;19(2):491-7. PMID:1676660
Crisnatol Preparation Products And Raw materials
Raw materials
Preparation Products
Crisnatol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 9995 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50068 | 58 |
