Pht-Gly-OtBu
- CAS No.
- 6297-93-4
- Chemical Name:
- Pht-Gly-OtBu
- Synonyms
- tert-Butyl 2-(1,3-dioxoisoindolin-2-yl)acetate;NSC126801;Pht-Gly-OtBu;Pht-Gly-OtBu-OH;Pht-Gly-OtBu 98%;PHTHALYL-GLYCINE T-BUTYL ESTER;Phthaloyl-glycinetertutylester;PHTHALOYL-GLYCINE T-BUTYL ESTER;Phthaloyl-glycine tert·butyl ester;N-PHTHALOYLGLYCINE TERT.-BUTYL ESTER
- CBNumber:
- CB0119353
- Molecular Formula:
- C14H15NO4
- Molecular Weight:
- 261.27
- MDL Number:
- MFCD00023082
- MOL File:
- 6297-93-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330 |
Pht-Gly-OtBu price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S671657 | N-PHTHALOYLGLYCINE TERT.-BUTYL ESTER AldrichCPR | 6297-93-4 | 1 unit | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | S671657 | N-PHTHALOYLGLYCINE TERT.-BUTYL ESTER AldrichCPR | 6297-93-4 | 250MG | $110 | 2024-03-01 | Buy |
| ChemScene | CS-0154831 | tert-Butyl 2-(1,3-dioxoisoindolin-2-yl)acetate ≥98% | 6297-93-4 | 1g | $16 | 2026-06-04 | Buy |
| ChemScene | CS-0154831 | tert-Butyl 2-(1,3-dioxoisoindolin-2-yl)acetate ≥98% | 6297-93-4 | 5g | $24 | 2026-06-04 | Buy |
| ChemScene | CS-0154831 | tert-Butyl 2-(1,3-dioxoisoindolin-2-yl)acetate ≥98% | 6297-93-4 | 10g | $47 | 2026-06-04 | Buy |
Pht-Gly-OtBu Chemical Properties, Uses, Production
Synthesis
5292-43-3
1074-82-4
6297-93-4
A 250 mL three-necked flask was equipped with a thermocouple, nitrogen inlet tube and magnetic stirrer and tert-butyl bromoacetate (10 g, 51 mmol) was added. Subsequently, acetone (100 mL) was added as a solvent and tetrabutylammonium bromide (0.8 g, 2.5 mmol) was added as a phase transfer catalyst. The potassium salt of phthalimide was added all at once and the reaction system was heated to 45 °C and maintained for 15 hours. Upon completion of the reaction, the mixture was cooled to 21 °C and concentrated by rotary evaporator to remove acetone. Ethyl acetate (100 mL) and water (30 mL) were added to the concentrate and stirred at 21 °C for 20 min to achieve phase separation. The organic layer was separated and washed sequentially with saturated sodium carbonate solution (3 x 30 mL) and brine. The organic phase was concentrated to remove volatile solvents. The crude product was suspended in ethanol (30 mL) and water (30 mL) was added slowly for 30 minutes. The suspension was stirred overnight at 21 °C, followed by collection of the solid product by filtration and washing with water to give the final tert-butyl 2-(1,3-dioxoisoindolin-2-yl)acetate in 78.4% isolated yield and 99.29% HPLC purity.
References
[1] Heterocycles, 2010, vol. 80, # 2, p. 989 - 1002
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 23, p. 6209 - 6217
Pht-Gly-OtBu Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Sichuan jiayinglai technology CO.,LTD | 9018 15982359653 | 1394531348@qq.com | China | 2271 | 55 |
| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
| 3A Chemicals | 400-668-9898 | service@3achem.com | China | 20535 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9533 | 58 |
View Latest Price from Pht-Gly-OtBu manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | Pht-Gly-OtBu
6297-93-4
|
1kg | 98% 99+ | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd |
-
- Pht-Gly-OtBu
6297-93-4
- 98% 99+
- Sichuan HongRi Pharma-Tech Co.,Ltd
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