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ChemicalBook >> CAS DataBase List >>Benzamide, 4-(9-acridinylamino)-N-hydroxy-

Benzamide, 4-(9-acridinylamino)-N-hydroxy-

Benzamide, 4-(9-acridinylamino)-N-hydroxy- Structure
Benzamide, 4-(9-acridinylamino)-N-hydroxy- structure
CAS No.
2413603-10-6
Chemical Name:
Benzamide, 4-(9-acridinylamino)-N-hydroxy-
Synonyms
HDAC6-IN-6;Benzamide, 4-(9-acridinylamino)-N-hydroxy-
CBNumber:
CB012004690
Molecular Formula:
C20H15N3O2
Molecular Weight:
329.35
MDL Number:
MOL File:
2413603-10-6.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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Benzamide, 4-(9-acridinylamino)-N-hydroxy- Properties

Density 1.382±0.06 g/cm3(Predicted)
pka 9.06±0.10(Predicted)

Benzamide, 4-(9-acridinylamino)-N-hydroxy- Chemical Properties,Uses,Production

Uses

HDAC6-IN-6 (compound 6a) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC50 of 0.025 μM. HDAC6-IN-6 exhibits strong inhibitory activity against Aβ1-42 self-aggregation and AChE, with IC50 values of 3.0 and 0.72 μM. HDAC6-IN-6 can enhance neurite outgrowth without significant neurotoxicity[1].

IC 50

HDAC6: 0.025 ± 0. μM (IC50); HDAC1: 0.34 ± 0.0 μM (IC50); HDAC: 0.55 ± 0.0 μM (IC50); HDAC9: 0.57 ± 0.0 μM (IC50); HDAC7: 0.65 ± 0.0 μM (IC50); HDAC5: 0.85 ± 0.0 μM (IC50); HDAC3: 1.22 ± 0.0 μM (IC50); HDAC2: 1.57 ± 0.0 μM (IC50); HDAC4: 2.24 ± 0.0 μM (IC50)

References

[1] Tseng HJ, et al. Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease. Eur J Med Chem. 2020 Apr 15;192:112193. DOI:10.1016/j.ejmech.2020.112193

Benzamide, 4-(9-acridinylamino)-N-hydroxy- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, 4-(9-acridinylamino)-N-hydroxy- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4960 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Lastest Price from Benzamide, 4-(9-acridinylamino)-N-hydroxy- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
HDAC6-IN-6 pictures 2026-04-20 HDAC6-IN-6
2413603-10-6
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • HDAC6-IN-6 pictures
  • HDAC6-IN-6
    2413603-10-6
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

2413603-10-6(Benzamide, 4-(9-acridinylamino)-N-hydroxy-)Related Search:

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Benzamide, 4-(9-acridinylamino)-N-hydroxy- HDAC6-IN-6 2413603-10-6