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ChemicalBook >> CAS DataBase List >>1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]-

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]-

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- Structure
1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- structure
CAS No.
2284460-01-9
Chemical Name:
1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]-
Synonyms
MC2590;1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]-
CBNumber:
CB012900345
Molecular Formula:
C20H17N3O3
Molecular Weight:
347.37
MDL Number:
MOL File:
2284460-01-9.mol
MSDS File:
SDS
Last updated:2026-08-30 11:39:11
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1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- Properties

Density 1.362±0.06 g/cm3(Predicted)
pka 8.63±0.23(Predicted)

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0635931 MC2590 98.71% 2284460-01-9 1mg $455 2026-06-04 Buy
ChemScene CS-0635931 MC2590 98.71% 2284460-01-9 5mg $921 2026-06-04 Buy
ChemScene CS-0635931 MC2590 98.71% 2284460-01-9 10mg $1284 2026-06-04 Buy
ChemScene CS-0635931 MC2590 98.71% 2284460-01-9 25mg $2058 2026-06-04 Buy
ChemScene CS-0635931 MC2590 98.71% 2284460-01-9 50mg $2871 2026-06-04 Buy
Product number Packaging Price Buy
CS-0635931 1mg $455 Buy
CS-0635931 5mg $921 Buy
CS-0635931 10mg $1284 Buy
CS-0635931 25mg $2058 Buy
CS-0635931 50mg $2871 Buy

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- Chemical Properties, Uses, Production

Uses

MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is a inhibitor of HDAC1-3, -6, -8, and -10 (class I/IIb-selective inhibitor) with IC50s of 0.015 μM-0.156 μM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 μM-3.98 μM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction[1].

IC 50

HDAC1: 0.098 μM (IC50); HDAC2: 0.156 μM (IC50); HDAC3: 0.039 μM (IC50); HDAC6: 0.015 μM (IC50); HDAC8: 0.047 μM (IC50); HDAC10: 0.071 μM (IC50); HDAC4: 2.73 μM (IC50); HDAC5: 1.35 μM (IC50); HDAC7: 2.06 μM (IC50); HDAC9: 2.79 μM (IC50); HDAC11: 3.98 μM (IC50)

References

[1] Elisabetta Di Bello, et al. Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells. Eur J Med Chem. 2022 Dec 15;247:115022. DOI:10.1016/j.ejmech.2022.115022

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- Suppliers

Global Suppliers ( 8)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
TargetMol Chemicals Inc. 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Amole Biotechnology Co., Ltd. 58

View Latest Price from 1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MC2590 pictures 2026-08-30 MC2590
2284460-01-9
 $208.00-942.00 99.64% 10g TargetMol Chemicals Inc.
  • MC2590 pictures
  • MC2590
    2284460-01-9
  • $208.00-942.00
  • 99.64%
  • TargetMol Chemicals Inc.

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- Spectrum

1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]-(2284460-01-9)1HNMR

2284460-01-9 (1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]-) Related Search:

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1-Naphthaleneacetamide, N-[6-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-3-pyridinyl]- MC2590 2284460-01-9