2-Chloro-5-benzothiazolamine
- CAS No.
- 80945-82-0
- Chemical Name:
- 2-Chloro-5-benzothiazolamine
- Synonyms
- 2-chlorobenzo[d]thiazol-5-amine;2-CHLORO-5-BENZOTHIAZOLAMINE;5-Amino-2-chlorobenzothiazole;5-Benzothiazolamine, 2-chloro-;5-AMino-2-chlorobenzo[d]thiazole;5-Amino-2-chloro-5-benzothiazole;5-Amino-2-chlorobenzothiazole 98%;2-chloro-1,3-benzothiazol-4-aMine;5-Benzothiazolamine,2-chloro-(9CI)
- CBNumber:
- CB01296284
- Molecular Formula:
- C7H5ClN2S
- Molecular Weight:
- 184.65
- MDL Number:
- MFCD11040282
- MOL File:
- 80945-82-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H302-H312-H332-H335-H319 |
| Precautionary statements | P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2934208090 |
2-Chloro-5-benzothiazolamine price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 073526 | 5-Amino-2-chlorobenzothiazole | 80945-82-0 | 250.00mg | $278 | 2026-05-18 | Buy |
| Matrix Scientific | 073526 | 5-Amino-2-chlorobenzothiazole | 80945-82-0 | 1.00g | $599 | 2026-05-18 | Buy |
| Matrix Scientific | 073526 | 5-Amino-2-chlorobenzothiazole | 80945-82-0 | 5.00g | $1643 | 2026-05-18 | Buy |
| Synthonix | A44787 | 5-Amino-2-chlorobenzothiazole 98% | 80945-82-0 | 100mg | $22 | 2026-05-06 | Buy |
| Synthonix | A44787 | 5-Amino-2-chlorobenzothiazole 98% | 80945-82-0 | 250mg | $28 | 2026-05-06 | Buy |
2-Chloro-5-benzothiazolamine Chemical Properties, Uses, Production
Synthesis
3622-38-6
80945-82-0
General procedure for the synthesis of 2-chloro-5-aminobenzothiazole from 2-chloro-5-nitrobenzo[d]thiazole: 1. In a reaction flask, 2-chloro-5-nitrobenzo[d]thiazole (2.18 g, 10.2 mmol) was dissolved in a solvent mixture of EtOH:acetic acid (91:9, 102 mL). 2. Iron powder (5.70 g, 102 mmol) was carefully added to the above solution and the reaction mixture was heated to reflux for 1.5 hours. 3. After completion of the reaction, the reaction mixture was filtered while hot to remove insoluble matter. 4. The filtrate was concentrated under reduced pressure to about one-third of the original volume. 5. The pH of the concentrate was adjusted to 8 with 10% aqueous NaOH. 6. 6. The mixture was extracted with ethyl acetate (150 mL) and the organic layer was separated. 7. The organic layer was washed with saturated saline, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. 8. The crude product was suspended in ethanol (4 mL), filtered, washed with a small amount of ethanol (0.5 mL) and dried to give 2-chloro-5-aminobenzothiazole (1.55 g) solid. LC-MS: tR = 0.78 min; [M + H]+ = 185.03. 1H NMR (400 MHz, D6-DMSO) δ: 7.65 (d, J = 8.7 Hz, 1H), 7.06 (d, J = 1.9 Hz, 1H), 6.79 (dd, J1 = 2.0 Hz, J2 = 8.7 Hz, 1H), 5.43 (s, 2H).
References
[1] Journal of medicinal chemistry, 1972, vol. 15, # 5, p. 523 - 529
[2] Patent: WO2016/207785, 2016, A1. Location in patent: Page/Page column 46
2-Chloro-5-benzothiazolamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. | 21-54820552 17702105771 | 188738128@qq.com | China | 300 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Jinan HM Medical Technology Co., Ltd. | 0531-88262980 13156180564 | jnhengmao@163.com | China | 100 | 62 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Yolne Chemical Co., Ltd. | 021-62960152 | 934678158@qq.com | China | 9886 | 55 |
View Latest Price from 2-Chloro-5-benzothiazolamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 2-Chloro-5-benzothiazolamine
80945-82-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-Chloro-5-benzothiazolamine
80945-82-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
