Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
- CAS No.
- 3622-38-6
- Chemical Name:
- Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
- Synonyms
- 2-Chloro-5-nitrobenzothiazole;2-chloro-5-nitrobenzo[d]thiazole;Benzothiazole, 2-chloro-5-nitro-;2-chloro-5-nitro-1,3-benzothiazole;Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
- CBNumber:
- CB41050109
- Molecular Formula:
- C7H3ClN2O2S
- Molecular Weight:
- 214.63
- MDL Number:
- MFCD09540490
- MOL File:
- 3622-38-6.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 29342000 |
Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 085526 | 2-Chloro-5-nitro-1,3-benzothiazole | 3622-38-6 | 250.00mg | $31 | 2026-05-18 | Buy |
| Matrix Scientific | 085526 | 2-Chloro-5-nitro-1,3-benzothiazole | 3622-38-6 | 1.00g | $56 | 2026-05-18 | Buy |
| Matrix Scientific | 085526 | 2-Chloro-5-nitro-1,3-benzothiazole | 3622-38-6 | 5.00g | $186 | 2026-05-18 | Buy |
| Synthonix | C44064 | 2-Chloro-5-nitrobenzo[d]thiazole 97% | 3622-38-6 | 250mg | $35 | 2026-05-06 | Buy |
| Synthonix | C44064 | 2-Chloro-5-nitrobenzo[d]thiazole 97% | 3622-38-6 | 1g | $41 | 2026-05-06 | Buy |
Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) Chemical Properties, Uses, Production
Synthesis
58759-63-0
3622-38-6
General method: GP3-1: A solution of 5-nitrobenzothiazole-2-thiol (1.0 eq.) with potassium ethylxanthate (1.2 eq. or 2.2 eq., 2.2 eq. is usually used) in 10 volumes of anhydrous DMF was heated for 4 hr. at 100 °C or 120 °C in a nitrogen atmosphere. The reaction progress was monitored by TLC. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with water (10 volumes), and neutralized with 1 M HCl solution to pH 5. The precipitate formed was collected by filtration, washed with water, and dried using a rotary evaporator followed by vacuum drying.GP3-2: Thionyl chloride (SO2Cl2, 1 volume) was slowly added to a mixture of 2-mercaptobenzothiazolyl chloride (2.2 eq.) containing 2-mercaptobenzothiazole (1.0 equivalent) in 2 volumes of anhydrous DCM solution. The mixture was stirred at room temperature for 1 h. The reaction progress was monitored by TLC. After the raw materials were consumed, the reaction mixture was diluted with 30 volumes of ether and the reaction was quenched by careful addition of water. Stirring was continued for 1 hour to ensure complete consumption of thionyl chloride and product release. The organic layer was separated, neutralized with saturated NaHCO3 solution, dried over Na2SO4 and subsequently purified by silica gel column chromatography to give the pure product. The final product was characterized by LC-MS and NMR.
References
[1] Journal of Heterocyclic Chemistry, 2005, vol. 42, # 4, p. 727 - 730
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 24, p. 7661 - 7670
[3] Patent: WO2016/207785, 2016, A1. Location in patent: Page/Page column 45; 46
Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. | 21-54820552 17702105771 | 188738128@qq.com | China | 300 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Jinan HM Medical Technology Co., Ltd. | 0531-88262980 13156180564 | jnhengmao@163.com | China | 100 | 62 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
View Latest Price from Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
3622-38-6
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
![2-Chloro-5-nitrobenzo[d]thiazole pictures](/ProductImageEN/2024-07/Small/40fec0d5-b680-470c-b869-db673b32a794.png) |
2024-07-15 | 2-Chloro-5-nitrobenzo[d]thiazole
3622-38-6
|
$1.00 | 1KG | 99% | 20t | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-04-22 | 2-Chloro-5-nitrobenzothiazole
3622-38-6
|
98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd |
-
- Benzothiazole, 2-chloro-5-nitro- (7CI,8CI,9CI)
3622-38-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Chloro-5-nitrobenzo[d]thiazole
3622-38-6
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Chloro-5-nitrobenzothiazole
3622-38-6
- 98%min
- Shanghai Rlavie Technology Co ltd
