6-Anilino-5,8-quinolinedione
- CAS No.
- 91300-60-6
- Chemical Name:
- 6-Anilino-5,8-quinolinedione
- Synonyms
- LY 83583;LY-83583 (LY83583);LY83583, 10 mM in DMSO;6-Anilino-5,8-quinolinedione;6-(anilino)quinoline-5,8-dione;6-ANILINOQUINOLINE-5,8-QUINONE;6-ANILINO-5,8-QUINOLINEQUINONE;6-(PHENYLAMINO)-5,8-QUINOLINEDIONE;6-(phenylamino)quinoline-5,8-dione;5,8-Quinolinedione, 6-(phenylamino)-
- CBNumber:
- CB0130280
- Molecular Formula:
- C15H10N2O2
- Molecular Weight:
- 250.25
- MDL Number:
- MFCD00210756
- MOL File:
- 91300-60-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 184-185°C |
|---|---|
| Boiling point | 446.9±45.0 °C(Predicted) |
| Density | 1.400±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | 0.1 M HCl: 1 mg/mL |
| form | solid |
| pka | -0.63±0.20(Predicted) |
| color | violet |
| InChI | 1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H |
| InChIKey | GXIJYWUWLNHKNW-UHFFFAOYSA-N |
| SMILES | O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13 |
| CAS DataBase Reference | 91300-60-6(CAS DataBase Reference) |
| FDA UNII | TD9FS56333 |
| UNSPSC Code | 41106305 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P271 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 40-36/37/38 | |||||||||
| Safety Statements | 36/37-36-26 | |||||||||
| WGK Germany | 2 | |||||||||
| HS Code | 2933499090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
6-Anilino-5,8-quinolinedione price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A6563 | 6-Anilinoquinoline-5,8-quinone ≥95% (TLC), solid | 91300-60-6 | 5mg | $161 | 2026-04-30 | Buy |
| Sigma-Aldrich | 440205-M | LY 83583 - CAS 91300-60-6 - Calbiochem A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC?? = 2 μM). | 91300-60-6 | 5mg | $116 | 2026-04-30 | Buy |
| Sigma-Aldrich | 440205-M | LY 83583 A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC₅₀ = 2 µM). | 91300-60-6 | 1 unit | $108 | 2025-07-31 | Buy |
| Sigma-Aldrich | 440205-M | LY 83583 | 91300-60-6 | 5mg-m | $101 | 2021-12-16 | Buy |
| Cayman Chemical | 70230 | LY83583 ≥99% | 91300-60-6 | 1mg | $20 | 2026-04-30 | Buy |
6-Anilino-5,8-quinolinedione Chemical Properties,Uses,Production
Chemical Properties
Red-Brown Solid
Uses
Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release
Uses
Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2μM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
Uses
LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 μM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 μM.[Cayman Chemical]
Definition
ChEBI: A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
Biological Activity
Primary Target
soluble guanylate cyclase', 'Target IC50: 2 μM against soluble guanylate cyclase
6-Anilino-5,8-quinolinedione Preparation Products And Raw materials
Raw materials
Preparation Products
6-Anilino-5,8-quinolinedione Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4484 | 50 | |
| Shanghai Meishui Chemical Technology Co., Ltd | 021-60549325 18616193163 | China | 4518 | 56 | |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2374 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4861 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Lastest Price from 6-Anilino-5,8-quinolinedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | LY83583
91300-60-6
|
$55.00-178.00 | 99.80% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-08-11 | 6-ANILINO-5,8-QUINOLINEDIONE
91300-60-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- LY83583
91300-60-6
- $55.00-178.00
- 99.80%
- TargetMol Chemicals Inc.
-
- 6-ANILINO-5,8-QUINOLINEDIONE
91300-60-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
