4-amidinoindan-1-one 2'-amidinohydrazone
- CAS No.
- 149400-88-4
- Chemical Name:
- 4-amidinoindan-1-one 2'-amidinohydrazone
- Synonyms
- SardoMozide;SAM 486A;CGP 48664;Sardomozide (CGP-48664;4-amidinoindan-1-one 2'-amidinohydrazone;(E)-2-(4-carbaMiMidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinec;2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide;(E)-2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide;Hydrazinecarboximidamide, 2-[4-(aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene]-
- CBNumber:
- CB01356458
- Molecular Formula:
- C11H14N6
- Molecular Weight:
- 230.27
- MDL Number:
- MFCD00920906
- MOL File:
- 149400-88-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 438.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.54±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Soluble in DMSO |
| pka | 11.54±0.20(Predicted) |
| NCI Dictionary of Cancer Terms | CGP 48664 |
| FDA UNII | CEB05S0B9I |
4-amidinoindan-1-one 2'-amidinohydrazone price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0007772 | Sardomozide 98.85% | 149400-88-4 | 5mg | $130 | 2026-06-04 | Buy |
| ChemScene | CS-0007772 | Sardomozide 98.85% | 149400-88-4 | 10mg | $217 | 2026-06-04 | Buy |
| ChemScene | CS-0007772 | Sardomozide 98.85% | 149400-88-4 | 25mg | $431 | 2026-06-04 | Buy |
| ChemScene | CS-0007772 | Sardomozide 98.85% | 149400-88-4 | 50mg | $690 | 2026-06-04 | Buy |
| ChemScene | CS-0007772 | Sardomozide 98.85% | 149400-88-4 | 100mg | $1105 | 2026-06-04 | Buy |
4-amidinoindan-1-one 2'-amidinohydrazone Chemical Properties, Uses, Production
Uses
Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
Biological Activity
Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM.
in vitro
Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC 50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.
target
IC50: 5 nM (SAMDC)
References
[1] Regenass U, et al. CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity. Cancer Res. 1994 Jun 15;54(12):3210-7. PMID:8205541
[2] Kramer DL, et al. Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664. Cancer Res. 1998 Sep 1;58(17):3883-90. PMID:9731498
4-amidinoindan-1-one 2'-amidinohydrazone Preparation Products And Raw materials
Raw materials
Preparation Products
4-amidinoindan-1-one 2'-amidinohydrazone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9787 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Twochem Co.Ltd. | 021-58111628 15800915896 | sales@twochem.com | China | 1782 | 58 |
| Tianjin Kaifu Pharmaceutical Technology Co., Ltd. | 18081075745 | chemflowtech@sina.com | China | 1883 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15030 | 58 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16103 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
View Latest Price from 4-amidinoindan-1-one 2'-amidinohydrazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | Sardomozide
149400-88-4
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-08-22 | Sardomozide
149400-88-4
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Sardomozide
149400-88-4
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- Sardomozide
149400-88-4
- $1520.00-2500.00
- TargetMol Chemicals Inc.
