2-naphthoylethyltrimethylammonium
- CAS No.
- 31059-54-8
- Chemical Name:
- 2-naphthoylethyltrimethylammonium
- Synonyms
- α-NETA;β-NETA;β-NETA, 10 mM in DMSO;2-naphthoylethyltrimethylammonium;alpha-NETA, Fluorescent ChAT inhibitor;2-(beta-Naphthoyl)ethyltrimethylammonium iodide;2-Dimethylaminoethyl 2-naphthyl ketone methiodide;trimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium:iodide;histamine,Cholinesterase (ChE),Apoptosis,ChE,β-NETA,KCl,β NETA,ChA,choline acetyltransferase,βNETA,Inhibitor,cholinesterase,inhibit
- CBNumber:
- CB01368697
- Molecular Formula:
- C16H20NO.I
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 31059-54-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| α-NETA ≥97% | 15125 | 5mg | $49 |
| α-NETA ≥97% | 15125 | 25mg | $178 |
| α-NETA ≥97% | 15125 | 5mg | $44 |
| α-NETA ≥97% | 15125 | 25mg | $161 |
| NETA alpha (2-(alpha-Naphthoyl)ethyltrimethylammonium iodide) ~97%(NMR) | 045076 | 5mg | $277 |
| More product size | |||
2-naphthoylethyltrimethylammonium price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15125 | α-NETA ≥97% | 31059-54-8 | 5mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 15125 | α-NETA ≥97% | 31059-54-8 | 25mg | $178 | 2026-04-30 | Buy |
| Cayman Chemical | 15125 | α-NETA ≥97% | 31059-54-8 | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 15125 | α-NETA ≥97% | 31059-54-8 | 25mg | $161 | 2024-03-01 | Buy |
| Usbiological | 045076 | NETA alpha (2-(alpha-Naphthoyl)ethyltrimethylammonium iodide) ~97%(NMR) | 31059-54-8 | 5mg | $277 | 2026-06-03 | Buy |
2-naphthoylethyltrimethylammonium Chemical Properties,Uses,Production
Description
Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-
Uses
Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.[Cayman Chemical]
Uses
alpha-NETA is a fluorescent choactase inhibitor.
IC 50
AChE
References
[1] B V SASTRY. 2-(alpha-Naphthoyl)ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase.[J]. Journal of Pharmacology and Experimental Therapeutics, 1988, 245 1: 72-80.
[2] B.V. RAMA SASTRY. Relationships between chemical structure and inhibition of choline acetyltransferase by 2-(α-naphthoyl)ethyltrimethylammonium and related compounds[J]. Pharmacological research communications, 1988, 20 9: Pages 751-771. DOI: 10.1016/s0031-6989(88)80715-x
[3] B.M. EATON S. R S. Regulation of the choline transport system in superfused microcarrier cultures of BeWo cells[J]. Placenta, 1998, 19 8: Pages 663-669. DOI: 10.1016/s0143-4004(98)90028-5
[4] DEBORAH A SAWATZKY. Eosinophil-induced release of acetylcholine from differentiated cholinergic nerve cells.[J]. American journal of physiology. Lung cellular and molecular physiology, 2003, 285 6: L1296-304. DOI: 10.1152/ajplung.00107.2003
2-naphthoylethyltrimethylammonium Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
