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2-naphthoylethyltrimethylammonium

CAS No.
31059-54-8
Chemical Name:
2-naphthoylethyltrimethylammonium
Synonyms
α-NETA;β-NETA;β-NETA, 10 mM in DMSO;2-naphthoylethyltrimethylammonium;alpha-NETA, Fluorescent ChAT inhibitor;2-(beta-Naphthoyl)ethyltrimethylammonium iodide;2-Dimethylaminoethyl 2-naphthyl ketone methiodide;trimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium:iodide;histamine,Cholinesterase (ChE),Apoptosis,ChE,β-NETA,KCl,β NETA,ChA,choline acetyltransferase,βNETA,Inhibitor,cholinesterase,inhibit
CBNumber:
CB01368697
Molecular Formula:
C16H20NO.I
Molecular Weight:
369.24
MDL Number:
MOL File:
31059-54-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

2-naphthoylethyltrimethylammonium Properties

storage temp. Store at -20°C, protect from light, stored under nitrogen
solubility DMSO: 3mg/ml; Methanol: Soluble
form A solid
color White to off-white

2-naphthoylethyltrimethylammonium price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 15125 α-NETA ≥97% 31059-54-8 5mg $49 2026-04-30 Buy
Cayman Chemical 15125 α-NETA ≥97% 31059-54-8 25mg $178 2026-04-30 Buy
Usbiological 045076 NETA alpha (2-(alpha-Naphthoyl)ethyltrimethylammonium iodide) ~97%(NMR) 31059-54-8 5mg $277 2026-06-03 Buy
Usbiological 045076 NETA alpha (2-(alpha-Naphthoyl)ethyltrimethylammonium iodide) ~97%(NMR) 31059-54-8 25mg $438 2026-06-03 Buy
ChemScene CS-0089727 β-NETA 98.0% 31059-54-8 5mg $55 2026-06-04 Buy
Product number Packaging Price Buy
15125 5mg $49 Buy
15125 25mg $178 Buy
045076 5mg $277 Buy
045076 25mg $438 Buy
CS-0089727 5mg $55 Buy

2-naphthoylethyltrimethylammonium Chemical Properties,Uses,Production

Description

Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.

Uses

Choline acetyltransferase (ChAT) mediates the synthesis of the neurotransmitter acetylcholine from acetyl-CoA and choline. In addition to its critical role in neurosignaling, deficiencies in ChAT are linked to congenital myasthenic syndromes, Alzheimer’s disease, and multiple sclerosis. α-NETA is a stable, non-competitive, and slowly reversible inhibitor of ChAT (IC50 = 9 μM). This naturally fluorescent compound is a poor inhibitor of cholinesterases and carnitine acetyltransferase. α-NETA is commonly used in cells in culture.[Cayman Chemical]

Uses

alpha-NETA is a fluorescent choactase inhibitor.

IC 50

AChE

References

[1] B V SASTRY. 2-(alpha-Naphthoyl)ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase.[J]. Journal of Pharmacology and Experimental Therapeutics, 1988, 245 1: 72-80.
[2] B.V. RAMA SASTRY. Relationships between chemical structure and inhibition of choline acetyltransferase by 2-(α-naphthoyl)ethyltrimethylammonium and related compounds[J]. Pharmacological research communications, 1988, 20 9: Pages 751-771. DOI: 10.1016/s0031-6989(88)80715-x
[3] B.M. EATON  S. R S. Regulation of the choline transport system in superfused microcarrier cultures of BeWo cells[J]. Placenta, 1998, 19 8: Pages 663-669. DOI: 10.1016/s0143-4004(98)90028-5
[4] DEBORAH A SAWATZKY. Eosinophil-induced release of acetylcholine from differentiated cholinergic nerve cells.[J]. American journal of physiology. Lung cellular and molecular physiology, 2003, 285 6: L1296-304. DOI: 10.1152/ajplung.00107.2003

2-naphthoylethyltrimethylammonium Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 36)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2936 58
hubei PharmaStandard Co., Ltd. 027-19050701 13545374703 cbbspring@163.com China 424 58

View Lastest Price from 2-naphthoylethyltrimethylammonium manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
β-NETA pictures 2026-07-27 β-NETA
31059-54-8
$30.00 98.00% 10g TargetMol Chemicals Inc.
β-NETA pictures 2026-07-27 β-NETA
31059-54-8
$30.00 98.00% 10g TargetMol Chemicals Inc.
β-NETA pictures 2026-06-30 β-NETA
31059-54-8
1KG 98% 20Tons Shaanxi Dideu New Materials Co. Ltd
  • β-NETA pictures
  • β-NETA
    31059-54-8
  • $30.00
  • 98.00%
  • TargetMol Chemicals Inc.
  • β-NETA pictures
  • β-NETA
    31059-54-8
  • $30.00
  • 98.00%
  • TargetMol Chemicals Inc.
  • β-NETA pictures
  • β-NETA
    31059-54-8
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd
2-naphthoylethyltrimethylammonium 2-(beta-Naphthoyl)ethyltrimethylammonium iodide 2-Dimethylaminoethyl 2-naphthyl ketone methiodide trimethyl-(3-naphthalen-2-yl-3-oxopropyl)azanium:iodide β-NETA α-NETA histamine,Cholinesterase (ChE),Apoptosis,ChE,β-NETA,KCl,β NETA,ChA,choline acetyltransferase,βNETA,Inhibitor,cholinesterase,inhibit alpha-NETA, Fluorescent ChAT inhibitor β-NETA, 10 mM in DMSO 31059-54-8